Edward D Plowey
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Explore the profile of Edward D Plowey including associated specialties, affiliations and a list of published articles.
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35
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4008
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Recent Articles
1.
Tien E, Grubor B, Kirkland M, Chan S, van der Munnik N, Xu W, et al.
Toxicol Pathol
. 2024 Feb;
52(1):35-54.
PMID: 38385340
Recombinant adeno-associated virus (AAV)-mediated degeneration of sensory neurons in the dorsal root ganglia (DRG) and trigeminal ganglia (TG) has been observed in non-human primates (NHPs) following intravenous (IV) and intrathecal...
2.
Guise A, Misal S, Carson R, Chu J, Boekweg H, Van Der Watt D, et al.
Cell Rep
. 2024 Jan;
43(1):113636.
PMID: 38183652
A limitation of conventional bulk-tissue proteome studies in amyotrophic lateral sclerosis (ALS) is the confounding of motor neuron (MN) signals by admixed non-MN proteins. Here, we leverage laser capture microdissection...
3.
Guise A, Misal S, Carson R, Boekweg H, Van Der Watt D, Truong T, et al.
bioRxiv
. 2023 Jun;
PMID: 37333094
Unbiased proteomics has been employed to interrogate central nervous system (CNS) tissues (brain, spinal cord) and fluid matrices (CSF, plasma) from amyotrophic lateral sclerosis (ALS) patients; yet, a limitation of...
4.
Plowey E, Bussiere T, Rajagovindan R, Sebalusky J, Hamann S, von Hehn C, et al.
Acta Neuropathol
. 2022 May;
144(1):143-153.
PMID: 35581440
Amyloid beta (Aβ) plaque is a defining pathologic feature of Alzheimer disease (AD). Aducanumab, a monoclonal IgG1 that selectively binds aggregated species of Aβ, has been shown by amyloid positron...
5.
Boekweg H, Van Der Watt D, Truong T, Johnston S, Guise A, Plowey E, et al.
J Proteome Res
. 2021 Dec;
21(1):182-188.
PMID: 34920664
The goal of proteomics is to identify and quantify the complete set of proteins in a biological sample. Single-cell proteomics specializes in the identification and quantitation of proteins for individual...
6.
Somebang K, Rudolph J, Imhof I, Li L, Niemi E, Shigenaga J, et al.
Cell Rep
. 2021 Sep;
36(12):109727.
PMID: 34551293
In traumatic brain injury (TBI), a diversity of brain resident and peripherally derived myeloid cells have the potential to worsen damage and/or to assist in healing. We define the heterogeneity...
7.
Cong Y, Motamedchaboki K, Misal S, Liang Y, Guise A, Truong T, et al.
Chem Sci
. 2021 Jun;
12(3):1001-1006.
PMID: 34163866
We report on the combination of nanodroplet sample preparation, ultra-low-flow nanoLC, high-field asymmetric ion mobility spectrometry (FAIMS), and the latest-generation Orbitrap Eclipse Tribrid mass spectrometer for greatly improved single-cell proteome...
8.
Berry K, Farias-Itao D, Grinberg L, Plowey E, Schneider J, Rodriguez R, et al.
ASN Neuro
. 2021 May;
13:17590914211018117.
PMID: 34056948
One hallmark of human aging is increased brain inflammation represented by glial activation. With age, there is also diminished function of the adaptive immune system, and modest decreases in circulating...
9.
Boekweg H, Guise A, Plowey E, Kelly R, Payne S
Mol Cell Proteomics
. 2021 Apr;
20:100085.
PMID: 33915259
Single-cell measurements are uniquely capable of characterizing cell-to-cell heterogeneity and have been used to explore the large diversity of cell types and physiological functions present in tissues and other complex...
10.
Jangam D, Sridhar K, Butzmann A, Samghabadi P, Plowey E, Ohgami R
Curr Eye Res
. 2020 Apr;
45(12):1583-1589.
PMID: 32339039
Purpose: Extranodal marginal zone B-cell lymphoma (EMZL) of mucosa-associated lymphoid tissue (MALT) that affects the ocular adnexa, also known as ocular adnexal MALT lymphomas (OAML), are low-grade lymphomas that mostly...