Edward Caddye
Overview
Explore the profile of Edward Caddye including associated specialties, affiliations and a list of published articles.
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4
Citations
107
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0
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Recent Articles
1.
Caddye E, Pineau J, Reyniers J, Ronen I, Colasanti A
Antioxidants (Basel)
. 2023 Sep;
12(9).
PMID: 37759960
Alterations in neurometabolism and mitochondria are implicated in the pathophysiology of psychiatric conditions such as mood disorders and schizophrenia. Thus, developing objective biomarkers related to brain mitochondrial function is crucial...
2.
Kidger A, Rushworth L, Stellzig J, Davidson J, Bryant C, Bayley C, et al.
Proc Natl Acad Sci U S A
. 2017 Jan;
114(3):E317-E326.
PMID: 28053233
Deregulated extracellular signal-regulated kinase (ERK) signaling drives cancer growth. Normally, ERK activity is self-limiting by the rapid inactivation of upstream kinases and delayed induction of dual-specificity MAP kinase phosphatases (MKPs/DUSPs)....
3.
Hoxhaj G, Caddye E, Najafov A, Houde V, Johnson C, Dissanayake K, et al.
Elife
. 2016 Jun;
5.
PMID: 27244671
The mechanistic Target of Rapamycin complex 1 (mTORC1) senses intracellular amino acid levels through an intricate machinery, which includes the Rag GTPases, Ragulator and vacuolar ATPase (V-ATPase). The membrane-associated E3...
4.
Rushworth L, Kidger A, Delavaine L, Stewart G, van Schelven S, Davidson J, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
111(51):18267-72.
PMID: 25489104
Ectopic expression of dual-specificity phosphatase 5 (DUSP5), an inducible mitogen-activated protein (MAP) kinase phosphatase, specifically inactivates and anchors extracellular signal-regulated kinase (ERK)1/2 in the nucleus. However, the role of endogenous...