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Edward C Hsiao

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Articles 86
Citations 2292
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Recent Articles
21.
Pignolo R, Baujat G, Hsiao E, Keen R, Wilson A, Packman J, et al.
J Bone Miner Res . 2022 Jul; 37(10):1891-1902. PMID: 35854638
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder characterized by progressive heterotopic ossification (HO), often heralded by flare-ups, leading to reduced movement and life expectancy. This placebo-controlled, double-blind trial...
22.
Eekhoff E, de Ruiter R, Smilde B, Schoenmaker T, de Vries T, Netelenbos C, et al.
Hum Gene Ther . 2022 May; 33(15-16):782-788. PMID: 35502479
Fibrodysplasia ossificans progressiva (FOP) is a rare and devastating genetic disease, in which soft connective tissue is converted into heterotopic bone through an endochondral ossification process. Patients succumb early as...
23.
Singh S, Morshed S, Motamedi D, Kidane J, Paul A, Hsiao E, et al.
J Clin Endocrinol Metab . 2022 Apr; 107(9):e3944-e3952. PMID: 35451005
Purpose: Heterotopic ossification (HO) is a process by which bone forms abnormally in soft tissues. Known risk factors for developing HO include male sex, spinal cord injury, trauma, and surgery....
24.
Yu X, Ton A, Niu Z, Morales B, Chen J, Braz J, et al.
Pain . 2022 Apr; 164(1):43-58. PMID: 35442931
Altered bone morphogenetic protein (BMP) signaling is associated with many musculoskeletal diseases. However, it remains unknown whether BMP dysfunction has direct contribution to debilitating pain reported in many of these...
25.
Kou S, Kile S, Kambampati S, Brady E, Wallace H, De Sousa C, et al.
Orphanet J Rare Dis . 2022 Mar; 17(1):107. PMID: 35246171
Background: COVID-19, caused by the SARS-CoV-2 virus, is a severe inflammatory condition. Patients with pre-existing conditions including diabetes, hypertension, and cardiovascular disease are at particularly high risk of complications. Fibrodysplasia...
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27.
de Ruiter R, Smilde B, Pals G, Bravenboer N, Knaus P, Schoenmaker T, et al.
Front Endocrinol (Lausanne) . 2021 Dec; 12:732728. PMID: 34858325
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare progressive genetic disease effecting one in a million individuals. During their life, patients with FOP progressively develop bone in the soft tissues resulting...
28.
Barruet E, Garcia S, Wu J, Morales B, Tamaki S, Moody T, et al.
Elife . 2021 Nov; 10. PMID: 34755602
Abnormalities in skeletal muscle repair can lead to poor function and complications such as scarring or heterotopic ossification (HO). Here, we use fibrodysplasia ossificans progressiva (FOP), a disease of progressive...
29.
Pignolo R, Hsiao E, Baujat G, Lapidus D, Sherman A, Kaplan F
Orphanet J Rare Dis . 2021 Aug; 16(1):350. PMID: 34353327
Background: Fibrodysplasia ossificans progressiva (FOP), an ultra-rare, progressive, and permanently disabling disorder of extraskeletal ossification, is characterized by episodic and painful flare-ups and irreversible heterotopic ossification in muscles, tendons, and...
30.
Warner S, Kaplan F, Pignolo R, Smith S, Hsiao E, De Cunto C, et al.
Calcif Tissue Int . 2021 Jul; 109(6):615-625. PMID: 34331548
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder that leads to heterotopic ossification (HO), resulting in progressive restriction of physical function. In this study, low-dose, whole-body computed tomography (WBCT)...