Edward C Hsiao
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Explore the profile of Edward C Hsiao including associated specialties, affiliations and a list of published articles.
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86
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Recent Articles
11.
Groeger M, Matsuo K, Heidary Arash E, Pereira A, Le Guillou D, Pino C, et al.
Nat Commun
. 2023 Jul;
14(1):3902.
PMID: 37400454
Hepatic insulin resistance is recognized as a driver of type 2 diabetes and fatty liver disease but specific therapies are lacking. Here we explore the potential of human induced pluripotent...
12.
Winger B, Devine W, Hsiao E, Zapala M, Van Ziffle J, Gupta N, et al.
Pediatr Blood Cancer
. 2023 Jun;
:e30516.
PMID: 37377128
Gorham-Stout disease (GSD) and generalized lymphatic anomaly (GLA) are subtypes of complex lymphatic malformations (CLMs) with osseous involvement that cause significant complications, including pain and pathologic fractures. As with other...
13.
Niu I, Hsiao E, Wustrack R, Wysolmerski J, Dann P, Masharani U
Calcif Tissue Int
. 2023 Jun;
113(2):246-253.
PMID: 37358786
The treatment of parathyroid hormone-related protein (PTHrP)-mediated hypercalcemia of malignancy includes treating the malignancy, intravenous fluids, and anti-resorptive therapies such as zoledronic acid or denosumab. PTHrP-mediated hypercalcemia has been reported...
14.
Chandran M, Alves I, Carpenter T, Davis M, Hsiao E, Petryk A, et al.
Osteoporos Int
. 2023 Jun;
34(8):1301-1310.
PMID: 37294334
Introduction: Rare bone diseases (RBDs) are a heterogenous group of disorders that are poorly understood and challenging to treat. This creates a plethora of unmet needs for people with RBDs...
15.
Lindborg C, Al Mukaddam M, Baujat G, Cho T, De Cunto C, Delai P, et al.
Clin Orthop Relat Res
. 2023 May;
481(12):2447-2458.
PMID: 37156007
Background: Fibrodysplasia ossificans progressiva (FOP) is an ultrarare genetic disorder with episodic and progressive heterotopic ossification. Tissue trauma is a major risk factor for flareups, heterotopic ossification (HO), and loss...
16.
Qi L, Matsuo K, Pereira A, Lee Y, Zhong F, He Y, et al.
Small
. 2023 Apr;
19(34):e2203725.
PMID: 37104853
Chronic white adipose tissue (WAT) inflammation has been recognized as a critical early event in the pathogenesis of obesity-related disorders. This process is characterized by the increased residency of proinflammatory...
17.
Wallace H, Lee R, Hsiao E
Orphanet J Rare Dis
. 2023 Mar;
18(1):61.
PMID: 36941608
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder associated with increased immune activity and severe, progressive heterotopic ossification. We previously described a cohort of 32 patients with FOP who...
18.
Pignolo R, Hsiao E, Al Mukaddam M, Baujat G, Berglund S, Brown M, et al.
J Bone Miner Res
. 2022 Dec;
38(3):381-394.
PMID: 36583535
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare, severely disabling genetic disorder of progressive heterotopic ossification (HO). The single-arm, open-label, phase 3 MOVE trial (NCT03312634) assessed efficacy and safety of palovarotene,...
19.
Wentworth K, Lalonde R, Groppe J, Brewer N, Moody T, Hansberry S, et al.
J Bone Miner Res
. 2022 Sep;
37(11):2058-2076.
PMID: 36153796
Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Overactivation can trigger heterotopic ossification (HO) as in fibrodysplasia ossificans progressiva (FOP), a rare, progressive disease of massive HO formation....
20.
Pignolo R, Baujat G, Brown M, De Cunto C, Hsiao E, Keen R, et al.
Genet Med
. 2022 Sep;
24(12):2422-2433.
PMID: 36152026
Purpose: We report the first prospective, international, natural history study of the ultra-rare genetic disorder fibrodysplasia ossificans progressiva (FOP). FOP is characterized by painful, recurrent flare-ups, and disabling, cumulative heterotopic...