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Edward C Hsiao

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Articles 86
Citations 2292
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Recent Articles
1.
Hsiao E, Pacifici M
JBMR Plus . 2024 Dec; 9(1):ziae147. PMID: 39677926
Retinoids are metabolic derivatives of vitamin A and play crucial roles in the regulation of various tissues and organs during prenatal and postnatal development. Active retinoids, like all-trans-retinoic acid, are...
2.
Hebert M, Babic K, Hsiao E, Afshar A, Acharya N, Gonzales J
Am J Ophthalmol Case Rep . 2024 Sep; 36:102167. PMID: 39314250
Purpose: To describe the use of anti-osteoclastic medications (i.e., bisphosphonates and receptor activator of nuclear factor kappa beta (RANK) ligand inhibitors) in treating choroidal osteoma. Methods: A 42-year-old male with...
3.
Qi L, Groeger M, Sharma A, Goswami I, Chen E, Zhong F, et al.
Nat Commun . 2024 Sep; 15(1):7991. PMID: 39266553
Interactions between adipose tissue, liver and immune system are at the center of metabolic dysfunction-associated steatotic liver disease and type 2 diabetes. To address the need for an accurate in...
4.
Patel A, Dada A, Saggi S, Yamada H, Ambati V, Goldstein E, et al.
Int J Spine Surg . 2024 Aug; PMID: 39191475
Patient-centric decision-making has imbued all aspects of health care, including spine surgery. This review describes how spine surgeons can use evolving technologies and knowledge of disease and pain states to...
5.
Haviv R, Zeitlin L, Moshe V, Ziv A, Rabinowicz N, De Benedetti F, et al.
Rheumatology (Oxford) . 2024 May; 63(9):2597-2604. PMID: 38733591
Objectives: Fibrodysplasia ossificans progressiva (FOP) is one of the most catastrophic forms of genetic heterotopic ossification (HO). FOP is characterized by severe, progressive inflammatory flare-ups, that often lead to HO....
6.
Lung H, Wentworth K, Moody T, Zamarioli A, Ram A, Ganesh G, et al.
JBMR Plus . 2024 Apr; 8(5):ziae011. PMID: 38577521
G protein-coupled receptors (GPCRs) mediate a wide spectrum of physiological functions, including the development, remodeling, and repair of the skeleton. Fibrous dysplasia (FD) of the bone is characterized by fibrotic,...
7.
Diolintzi A, Pervin M, Hsiao E
Biomolecules . 2024 Mar; 14(3). PMID: 38540775
Background: Inflammation is a major driver of heterotopic ossification (HO), a condition of abnormal bone growth in a site that is not normally mineralized. Purpose Of Review: This review will...
8.
Juan C, Bancroft A, Choi J, Nunez J, Pagani C, Lin Y, et al.
Biomolecules . 2024 Mar; 14(3). PMID: 38540768
Heterotopic ossification (HO) is a debilitating pathology where ectopic bone develops in areas of soft tissue. HO can develop as a consequence of traumatic insult or as a result of...
9.
Lounev V, Groppe J, Brewer N, Wentworth K, Smith V, Xu M, et al.
J Bone Miner Res . 2024 Mar; 39(4):382-398. PMID: 38477818
Single case studies of extraordinary disease resilience may provide therapeutic insight into conditions for which no definitive treatments exist. An otherwise healthy 35-year-old man (patient-R) with the canonical pathogenic ACVR1R206H...
10.
Pignolo R, Al Mukaddam M, Baujat G, Brown M, De Cunto C, Hsiao E, et al.
BMC Med Res Methodol . 2023 Nov; 23(1):269. PMID: 37957586
Background: The design of clinical trials in rare diseases is often complicated by a lack of real-world translational knowledge. Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder characterized by...