Edward C Goodwin
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Explore the profile of Edward C Goodwin including associated specialties, affiliations and a list of published articles.
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11
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1061
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Recent Articles
1.
Fournier M, Goodwin E, Chen J, Obenauer J, Tannenbaum S, Brufsky A
Sci Rep
. 2019 Oct;
9(1):14863.
PMID: 31619719
We developed a test to predict which patients will achieve pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) and which will have residual disease (RD). Gene expression data from pretreatment...
2.
Delmonico L, Attiya S, Chen J, Obenauer J, Goodwin E, Fournier M
Dis Markers
. 2019 Jun;
2019:1940347.
PMID: 31217830
Background: With the development of new drug combinations and targeted treatments for multiple types of cancer, the ability to stratify categories of patient populations and to develop companion diagnostics has...
3.
Popa A, Zhang W, Harrison M, Goodner K, Kazakov T, Goodwin E, et al.
PLoS Pathog
. 2015 Feb;
11(2):e1004699.
PMID: 25693203
Trafficking of human papillomaviruses to the Golgi apparatus during virus entry requires retromer, an endosomal coat protein complex that mediates the vesicular transport of cellular transmembrane proteins from the endosome...
4.
Goodwin E, Motamedi N, Lipovsky A, Fernandez-Busnadiego R, DiMaio D
PLoS One
. 2014 Apr;
9(4):e94322.
PMID: 24732912
DNAJB12 and DNAJB14 are transmembrane proteins in the endoplasmic reticulum (ER) that serve as co-chaperones for Hsc70/Hsp70 heat shock proteins. We demonstrate that over-expression of DNAJB12 or DNAJB14 causes the...
5.
Iijima N, Goodwin E, DiMaio D, Iwasaki A
Virology
. 2013 Jul;
444(1-2):257-62.
PMID: 23871219
High-risk human papillomaviruses (HPVs) cause a variety of malignancies of the mucosal epithelium. However, the local immune evasion strategies used by HPV-transformed cells remain unclear. Here, we examined the effect...
6.
Goodwin E, Lipovsky A, Inoue T, Magaldi T, Edwards A, Van Goor K, et al.
mBio
. 2011 Jun;
2(3):e00101-11.
PMID: 21673190
Simian virus 40 (SV40) is a nonenveloped DNA virus that traffics through the endoplasmic reticulum (ER) en route to the nucleus, but the mechanisms of capsid disassembly and ER exit...
7.
Goodwin E, Atwood W, DiMaio D
J Virol
. 2009 Mar;
83(11):5630-9.
PMID: 19297472
We developed a high-throughput, cell-based screen to identify chemicals that inhibit infection by the primate polyomaviruses. The screen is based on the detection of compounds that inhibit the ability of...
8.
Johung K, Goodwin E, DiMaio D
J Virol
. 2006 Dec;
81(5):2102-16.
PMID: 17182682
This work demonstrates a central role for the retinoblastoma (Rb) family in driving the transcriptional program of induced and replicative senescence. HeLa cervical carcinoma cells rapidly undergo senescence when the...
9.
Lee B, Han J, Im J, Morrone A, Johung K, Goodwin E, et al.
Aging Cell
. 2006 Apr;
5(2):187-95.
PMID: 16626397
Replicative senescence limits the proliferation of somatic cells passaged in culture and may reflect cellular aging in vivo. The most widely used biomarker for senescent and aging cells is senescence-associated...
10.
Brandsma J, Shlyankevich M, Zhang L, Slade M, Goodwin E, Peh W, et al.
J Virol
. 2003 Dec;
78(1):116-23.
PMID: 14671093
Cervical cancer arises from lesions caused by infection with high-risk types of human papillomavirus (HPV). Therefore, vaccination against HPV could prevent carcinogenesis by preventing HPV infection or inducing lesion regression....