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Eduardo Lazarowski

Explore the profile of Eduardo Lazarowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 264
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Recent Articles
1.
Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, et al.
J Immunol . 2012 Jul; 189(4):1992-9. PMID: 22778393
GPR105, a G protein-coupled receptor for UDP-glucose, is highly expressed in several human tissues and participates in the innate immune response. Because inflammation has been implicated as a key initial...
2.
Davis C, Lazarowski E
Respir Physiol Neurobiol . 2008 Jul; 163(1-3):208-13. PMID: 18635403
The mucociliary clearance system is comprised of three components, ion transport activities controlling the height of airway surface liquid (ASL), mucin secretion, and ciliary activity. These activities in humans are...
3.
Tatur S, Kreda S, Lazarowski E, Grygorczyk R
Purinergic Signal . 2008 Mar; 4(2):139-46. PMID: 18368524
Extracellular nucleotides play an important role in lung defense, but the release mechanism and relative abundance of different nucleotide species secreted by lung epithelia are not well defined. In this...
4.
Lazarowski E
Novartis Found Symp . 2006 Jun; 276:73-84. PMID: 16805424
ATP is co-stored in neurosecretory vesicles together with aminergic compounds and is released from neural cells and synaptic terminals via regulated exocytosis. ATP also is released from non-neuronal cells including...
5.
Wihlborg A, Balogh J, Wang L, Borna C, Dou Y, Joshi B, et al.
Circ Res . 2006 Mar; 98(7):970-6. PMID: 16543499
The aim of this study was to examine a possible role for extracellular pyrimidines as inotropic factors for the heart. First, nucleotide plasma levels were measured to evaluate whether UTP...
6.
Borna C, Lazarowski E, van Heusden C, Ohlin H, Erlinge D
Thromb J . 2005 Jul; 3:10. PMID: 16045804
Background: To be fully activated platelets are dependent on two positive feedback loops; the formation of thromboxane A2 by cyclooxygenase in the platelets and the release of ADP. We wanted...
7.
Erlinge D, Harnek J, van Heusden C, Olivecrona G, Jern S, Lazarowski E
Int J Cardiol . 2005 Apr; 100(3):427-33. PMID: 15837087
Background: Extracellular uridine triphosphate (UTP) stimulates vasodilatation, automaticity in ventricular myocytes and release of tissue-plasminogen activator (t-PA), indicating that UTP may be important in cardiac regulation. We took advantage of...
8.
Spychala J, Lazarowski E, Ostapkowicz A, Ayscue L, Jin A, Mitchell B
Clin Cancer Res . 2004 Feb; 10(2):708-17. PMID: 14760094
Purpose: The purpose is to understand the expression of ecto-5'-nucleotidase (eN), an adenosine producing enzyme with potential roles in angiogenesis, growth, and immunosuppression, in estrogen receptor (ER)-negative and -positive breast...
9.
Hou M, Harden T, Kuhn C, Baldetorp B, Lazarowski E, Pendergast W, et al.
Am J Physiol Heart Circ Physiol . 2002 Jan; 282(2):H784-92. PMID: 11788430
Mitogenic effects of the extracellular nucleotides ATP and UTP are mediated by P2Y(1), P2Y(2), and P2Y(4) receptors. However, it has not been possible to examine the highly expressed UDP-sensitive P2Y(6)...