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Edroyal Womack

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Recent Articles
1.
Womack E, Antone M, Eichenbaum Z
Microbiol Spectr . 2024 Oct; :e0133124. PMID: 39470285
Importance: obtains growth essential iron from hemoglobin and other host hemoproteins. Still, the bacterial mechanisms involved are only partially understood, and there are inconsistent reports regarding the function of several...
2.
Womack E, Alibayov B, Vidal J, Eichenbaum Z
Microbiol Spectr . 2023 Dec; 12(1):e0329723. PMID: 38038454
Heme degradation provides pathogens with growth essential iron, leveraging on the host heme reservoir. Bacteria typically import and degrade heme enzymatically, and here, we demonstrated a significant deviation from this...
3.
Yu B, Roy Choudhury M, Yang X, Benoit S, Womack E, Lyles K, et al.
ACS Infect Dis . 2022 Jul; 8(8):1491-1508. PMID: 35801980
The rapid and persistent emergence of drug-resistant bacteria poses a looming public health crisis. The possible task of developing new sets of antibiotics to replenish the existing ones is daunting...
4.
Akhter F, Womack E, Vidal J, Le Breton Y, McIver K, Pawar S, et al.
Infect Immun . 2021 Jan; 89(4). PMID: 33397818
grows in biofilms during both asymptomatic colonization and infection. Pneumococcal biofilms on abiotic surfaces exhibit delayed growth and lower biomass and lack the structures seen on epithelial cells or during...
5.
Akhter F, Womack E, Vidal J, Le Breton Y, McIver K, Pawar S, et al.
Sci Rep . 2020 Sep; 10(1):15202. PMID: 32938947
Streptococcus pneumoniae (Spn) must acquire iron from the host to establish infection. We examined the impact of hemoglobin, the largest iron reservoir in the body, on pneumococcal physiology. Supplementation with...