Edith K Y Tang
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Explore the profile of Edith K Y Tang including associated specialties, affiliations and a list of published articles.
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26
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1138
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Recent Articles
1.
Slominski A, Kim T, Slominski R, Song Y, Janjetovic Z, Podgorska E, et al.
FASEB J
. 2022 Jul;
36(8):e22451.
PMID: 35838947
CYP11A1 and CYP27A1 hydroxylate tachysterol , a photoproduct of previtamin D , producing 20S-hydroxytachysterol [20S(OH)T ] and 25(OH)T , respectively. Both metabolites were detected in the human epidermis and serum....
2.
Slominski A, Brozyna A, Kim T, Elsayed M, Janjetovic Z, Qayyum S, et al.
Int J Oncol
. 2022 Jul;
61(2).
PMID: 35775377
Hydroxyderivatives of vitamin D3, including classical 1,25(OH)D3 and novel CYP11A1‑derived hydroxyderivatives, exert their biological activity by acting as agonists on the vitamin D receptor (VDR) and inverse agonists on retinoid‑related...
3.
Tang E, Partridge G, Woolley L, Pilmer L, Lim L
Mar Drugs
. 2022 May;
20(5).
PMID: 35621974
Praziquantel (PZQ) provides an effective treatment against monogenean parasitic infestations in finfish. However, its use as an in-feed treatment is challenging due to palatability issues. In this study, five formulations...
4.
Kim T, Atigadda V, Brzeminski P, Fabisiak A, Tang E, Tuckey R, et al.
ACS Food Sci Technol
. 2022 Apr;
1(7):1228-1235.
PMID: 35449872
Melatonin and serotonin, products of tryptophan metabolism, are endogenous neurotransmitters and hormones. We have identified and quantified these metabolites in natural honey from Australia, USA, and Poland using a Xevo...
5.
Tuckey R, Tang E, Chen Y, Slominski A
J Steroid Biochem Mol Biol
. 2021 Jun;
212:105929.
PMID: 34098080
7-Dehydrocholesterol reductase (DHCR7) catalyses the final step of cholesterol biosynthesis in the Kandutsch-Russel pathway, the reduction of 7-dehydrocholesterol (7DHC) to cholesterol. 7DHC can be acted on by a range of...
6.
Slominski A, Kim T, Qayyum S, Song Y, Janjetovic Z, Oak A, et al.
Sci Rep
. 2021 Apr;
11(1):8002.
PMID: 33850196
The interactions of derivatives of lumisterol (L3) and vitamin D3 (D3) with liver X receptors (LXRs) were investigated. Molecular docking using crystal structures of the ligand binding domains (LBDs) of...
7.
Chaiprasongsuk A, Janjetovic Z, Kim T, Schwartz C, Tuckey R, Tang E, et al.
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33317048
Lumisterol (L3) is a stereoisomer of 7-dehydrocholesterol and is produced through the photochemical transformation of 7-dehydrocholesteol induced by high doses of UVB. L3 is enzymatically hydroxylated by CYP11A1, producing 20(OH)L3,...
8.
Kim T, Atigadda V, Brzeminski P, Fabisiak A, Tang E, Tuckey R, et al.
Molecules
. 2020 Jun;
25(11).
PMID: 32498437
20()-Hydroxyvitamin D3 (20(OH)D3) is an endogenous metabolite produced by the action of CYP11A1 on the side chain of vitamin D3 (D3). 20(OH)D3 can be further hydroxylated by CYP11A1, CYP27A1, CYP24A1...
9.
Li H, Yan L, Tang E, Zhang Z, Chen W, Liu G, et al.
Front Pharmacol
. 2019 Jul;
10:769.
PMID: 31354485
Curcumin (CCM) has many potential uses in anticancer chemotherapy, but its low water solubility poses a major problem, preventing its translation into clinical use. TPGS is a water-soluble derivative of...
10.
Chaiprasongsuk A, Janjetovic Z, Kim T, Jarrett S, DOrazio J, Holick M, et al.
Redox Biol
. 2019 May;
24:101206.
PMID: 31039479
We tested whether novel CYP11A1-derived vitamin D- and lumisterol-hydroxyderivatives, including 1,25(OH)D, 20(OH)D, 1,20(OH)D, 20,23(OH)D, 1,20,23(OH)D, lumisterol, 20(OH)L, 22(OH)L, 20,22(OH)L, and 24(OH)L, can protect against UVB-induced damage in human epidermal keratinocytes....