E T Machuga
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Explore the profile of E T Machuga including associated specialties, affiliations and a list of published articles.
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4
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24
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Recent Articles
1.
Roth G, Machuga E, Ozols J
Biochemistry
. 1983 Sep;
22(20):4672-5.
PMID: 6414516
Aspirin (acetylsalicylic acid) inhibits prostaglandin synthesis by acetylating a single internal serine residue of the initial enzyme in the biosynthetic pathway, prostaglandin synthetase. In this study, the region of the...
2.
STRITTMATTER P, Machuga E, Roth G
J Biol Chem
. 1982 Oct;
257(20):11883-6.
PMID: 6811590
Prostaglandin synthetase has been reconstituted in dimyristyl phosphatidylcholine vesicles. These vesicles in either 80 or 2 microM flufenamate utilized NADH or NADPH as electron donor in the reductive peroxidative step...
3.
Roth G, Machuga E
J Lab Clin Med
. 1982 Feb;
99(2):187-96.
PMID: 6801166
Normal platelet function depends, in part, on platelet PG synthesis. PG synthetase (cyclo-oxygenase) catalyzes the first step in PG synthesis, the formation of PGH2 from arachidonic acid. Inhibition of the...
4.
Roth G, Machuga E, STRITTMATTER P
J Biol Chem
. 1981 Oct;
256(19):10018-22.
PMID: 6792194
Purified, apoprostaglandin synthetase was prepared from sheep vesicular gland and studied in terms of its heme-binding properties. The enzyme binds a single heme group per enzyme monomer, Mr = 70,000....