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E Sitnicka

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Recent Articles
1.
Adolfsson J, Borge O, Bryder D, Theilgaard-Monch K, Sitnicka E, Sasaki Y, et al.
Immunity . 2001 Oct; 15(4):659-69. PMID: 11672547
Flt3 has emerged as a potential regulator of hematopoietic stem cells (HSC). Sixty percent of cells in the mouse marrow Lin(-)Sca1(+)c-kit(+) HSC pool expressed flt3. Although single cell cloning showed...
2.
Yagi M, Ritchie K, Sitnicka E, Storey C, Roth G, Bartelmez S
Proc Natl Acad Sci U S A . 1999 Jul; 96(14):8126-31. PMID: 10393959
The hematopoietic stem cell (HSC) is defined as a cell that can either self-replicate or generate daughter cells that are destined to commit to mature cells of different specific lineages....
3.
Sitnicka E, Ruscetti F, Priestley G, WOLF N, Bartelmez S
Blood . 1996 Jul; 88(1):82-8. PMID: 8704205
Hematopoiesis appears to be regulated, in part, by a balance between extracellular positive and negative growth signals. Transforming growth factor beta-1 (TGF-beta 1) has been shown to be a negative...
4.
Sitnicka E, Lin N, Priestley G, Fox N, Broudy V, WOLF N, et al.
Blood . 1996 Jun; 87(12):4998-5005. PMID: 8652812
In this study, we explored whether thrombopoietin (Tpo) has a direct in vitro effect on the proliferation and differentiation of long-term repopulating hematopoietic stem cells (LTR-HSC). We previously reported a...
5.
Kaushansky K, Broudy V, Sitnicka E, Lofton-Day C, Grossmann A, Sprugel K
Stem Cells . 1996 Jan; 14 Suppl 1:108-11. PMID: 11012209
In the short time since its cloning, much has been learned of the in vitro properties of thrombopoietin (TPO). In addition to effects on the differentiation of megakaryocytes, TPO has...
6.
Sitnicka E, Wang Q, Tsai S, WOLF N
Stem Cells . 1995 Nov; 13(6):655-65. PMID: 8590867
Stromal cells are believed to regulate hematopoiesis through direct cell-cell contact interactions and the release of growth factors. Many questions remain, however, about their lineage derivation and functional heterogeneity. We...
7.
Tsai S, Bartelmez S, Sitnicka E, Collins S
Genes Dev . 1994 Dec; 8(23):2831-41. PMID: 7995521
The lymphohematopoietic progenitors represent < 0.01% of nucleated marrow cells. Here, we describe the immortalization of the murine lymphohematopoietic progenitors by a retroviral vector harboring a dominant-negative retinoic acid receptor....
8.
Keller J, Bartelmez S, Sitnicka E, Ruscetti F, Ortiz M, Gooya J, et al.
Blood . 1994 Oct; 84(7):2175-81. PMID: 7919333
Both transforming growth factor beta (TGF beta) and macrophage inflammatory protein 1 alpha (MIP-1 alpha) have been shown to be multifunctional regulators of hematopoiesis that can either inhibit or enhance...
9.
Pisa P, Sitnicka E, Hansson M
Scand J Immunol . 1993 Apr; 37(4):529-32. PMID: 8469936
The in vivo effect of natural killer (NK) cell activation on autologous myelopoiesis was studied in an environment deficient of functional T and B cells. Administration of 3,6-bis[2-(Dimethylamino)-ethoxy]-9H-xanthen-9-one dihydrochloride) Tilorone)...
10.
Penn P, Jiang D, Fei R, Sitnicka E, WOLF N
Blood . 1993 Mar; 81(5):1205-13. PMID: 8443381
We have previously shown the adherent nontransformed, nonimmortalized murine bone marrow stromal cell (BMSC) population to consist of phagocytic macrophage and endothelial-like cells and nonphagocytic fibroblasts. Both colonial and near...