E Scott Halstead
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Explore the profile of E Scott Halstead including associated specialties, affiliations and a list of published articles.
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42
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481
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Recent Articles
1.
Samuelsen A, Halstead E, Lehman E, McKeone D, Bonavia A
Crit Care Explor
. 2024 Jun;
6(7):e1106.
PMID: 38916619
Objectives: While cytokine response patterns are pivotal in mediating immune responses, they are also often dysregulated in sepsis and critical illness. We hypothesized that these immunological deficits, quantifiable through ex...
2.
Yehya N, Booth T, Ardhanari G, Thompson J, Lam L, Till J, et al.
J Clin Invest
. 2024 Apr;
134(10).
PMID: 38573766
BACKGROUNDThe molecular signature of pediatric acute respiratory distress syndrome (ARDS) is poorly described, and the degree to which hyperinflammation or specific tissue injury contributes to outcomes is unknown. Therefore, we...
3.
Hahn T, McKeone D, Beal J, Ericson J, Halstead E
Front Pediatr
. 2024 Feb;
11:1340360.
PMID: 38304439
We describe the case of an infant who presented with simple rhinovirus/enterovirus bronchiolitis whose condition worsened with rapid progression to multiple organ dysfunction syndrome (MODS). The patient was presumed to...
4.
Wheelwright J, Halstead E, Knehans A, Bonavia A
CHEST Crit Care
. 2023 Dec;
1(3).
PMID: 38148988
Background: Sepsis is a syndrome characterized by host immune dysfunction, with the extent of immunoparalysis differing among patients. Lipopolysaccharide (LPS) is used commonly to assess the immune function of critically...
5.
Yau E, Yang L, Chen Y, Umstead T, Stanley A, Halstead E, et al.
Microbes Infect
. 2023 Dec;
26(3):105280.
PMID: 38135024
Influenza A virus (IAV) infection causes acute and often lethal inflammation in the lung. The role of macrophages in this adverse inflammation is partially understood. The surfactant protein A receptor...
6.
Bonavia A, Samuelsen A, Liang M, Hanson J, McKeone D, Chroneos Z, et al.
Intensive Care Med Exp
. 2023 Oct;
11(1):70.
PMID: 37831231
Background: Sepsis is characterized by highly heterogeneous immune responses associated with a spectrum of disease severity. Methods that rapidly and sensitively profile these immune responses can potentially personalize immune-adjuvant therapies...
7.
Yehya N, Zinter M, Thompson J, Lim M, Hanudel M, Alkhouli M, et al.
Thorax
. 2023 Oct;
79(2):128-134.
PMID: 37813544
Background: Two subphenotypes of acute respiratory distress syndrome (ARDS), hypoinflammatory and hyperinflammatory, have been reported in adults and in a single paediatric cohort. The relevance of these subphenotypes in paediatrics...
8.
Han L, Wu X, Wang O, Luan X, Velander W, Aynardi M, et al.
Theranostics
. 2023 Jun;
13(9):2843-2862.
PMID: 37284443
Trauma, surgery, and infection can cause severe inflammation. Both dysregulated inflammation intensity and duration can lead to significant tissue injuries, organ dysfunction, mortality, and morbidity. Anti-inflammatory drugs such as steroids...
9.
Yau E, Yang L, Chen Y, Umstead T, Atkins H, Katz Z, et al.
Front Immunol
. 2023 Mar;
14:919800.
PMID: 36960051
Influenza A virus infection (IAV) often leads to acute lung injury that impairs breathing and can lead to death, with disproportionate mortality in children and the elderly. Surfactant Protein A...
10.
Nguyen J, Thompson J, Balcarcel D, Alder M, McKeone D, Halstead E, et al.
Crit Care Explor
. 2023 Jan;
5(1):e0844.
PMID: 36699254
Objectives: We aimed to identify a biomarker profile of immunocompromised children, with and without stem cell transplant, independent of illness severity. Design Settings And Participants: This was a secondary analysis...