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E R Pearson

Explore the profile of E R Pearson including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 890
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Recent Articles
1.
Obura M, Beulens J, Slieker R, Koopman A, Hoekstra T, Nijpels G, et al.
Diabet Med . 2020 Oct; 38(2):e14428. PMID: 33067862
Aim: To examine the hypothesis that, based on their glucose curves during a seven-point oral glucose tolerance test, people at elevated type 2 diabetes risk can be divided into subgroups...
2.
Noyes J, Soto-Pedre E, Donnelly L, Pearson E
Diabet Med . 2017 Jul; 35(2):262-269. PMID: 28755478
Aims: Increased visit-to-visit glycaemic variability is independently associated with adverse outcomes in Type 2 diabetes. Our aim was to identify the patient characteristics associated with raised visit-to-visit glycaemic variability in...
3.
Dujic T, Zhou K, Yee S, van Leeuwen N, de Keyser C, Javorsky M, et al.
Clin Pharmacol Ther . 2016 Nov; 101(6):763-772. PMID: 27859023
Therapeutic response to metformin, a first-line drug for type 2 diabetes (T2D), is highly variable, in part likely due to genetic factors. To date, metformin pharmacogenetic studies have mainly focused...
4.
Pearson E
Diabet Med . 2016 Jan; 33(6):712-7. PMID: 26802434
Personalized medicine, otherwise called stratified or precision medicine, aims to better target intervention to the individual to maximize benefit and minimize harm. This review discusses how diabetes aetiology, pathophysiology and...
5.
Connelly P, Smith N, Chadwick R, Exley A, Shneerson J, Pearson E
Diabet Med . 2015 Nov; 33(3):371-5. PMID: 26606753
Aim: To investigate glucose and insulin metabolism in participants with ataxia telangiectasia in the absence of a diagnosis of diabetes. Methods: A standard oral glucose tolerance test was performed in...
6.
Dujic T, Causevic A, Bego T, Malenica M, Velija-Asimi Z, Pearson E, et al.
Diabet Med . 2015 Nov; 33(4):511-4. PMID: 26605869
Aims: Metformin is the most widely used oral anti-diabetes agent and has considerable benefits over other therapies, yet 20-30% of people develop gastrointestinal side effects, and 5% are unable to...
7.
Yew T, McCreight L, Colclough K, Ellard S, Pearson E
Diabet Med . 2015 Nov; 33(9):e21-5. PMID: 26526202
Background: A syndrome of young-onset diabetes mellitus associated with microcephaly, epilepsy and intellectual disability caused by mutations in the tRNA methyltransferase 10 homologue A (TRMT10A) gene has recently been described....
8.
Macfarlane D, OSullivan E, Dorman S, Allison J, Ellingford A, Pearson E, et al.
Diabet Med . 2013 Feb; 30(8):1009-10. PMID: 23398520
No abstract available.
9.
Pearson E
J R Coll Physicians Edinb . 2012 Sep; 42(3):228. PMID: 22953318
There is an increase in type 2 diabetes (T2D) in children, yet little evidence to guide management. The TODAY study aimed to assess the impact of three treatment interventions in...
10.
George P, Pearson E, Witham M
Diabet Med . 2012 Apr; 29(8):e142-50. PMID: 22486204
Aims: To systematically review the evidence for the effect of vitamin D supplementation on glycaemia, insulin resistance, progression to diabetes and complications of diabetes. Methods: Systematic review and meta-analysis. We...