E P Merricks
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Explore the profile of E P Merricks including associated specialties, affiliations and a list of published articles.
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10
Citations
83
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0
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Recent Articles
1.
Maile L, Busby W, Xi G, Gollahan K, Flowers W, Gafbacik N, et al.
Atherosclerosis
. 2017 Feb;
258:40-50.
PMID: 28189040
Background And Aims: Diabetes is a major risk factor for the development of atherosclerosis. Hyperglycemia stimulates vascular smooth muscle cells (VSMC) to secrete ligands that bind to the αVβ3 integrin,...
2.
Agerso H, Stennicke H, Pelzer H, Olsen E, Merricks E, Defriess N, et al.
Haemophilia
. 2012 Jul;
18(6):941-7.
PMID: 22812621
The objective of the present study was to evaluate the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the new recombinant FVIII compound turoctocog alfa and a Glyco-PEGylated FVIII derivative thereof...
3.
Nolte M, Nichols T, Mueller-Cohrs J, Merricks E, Pragst I, Zollner S, et al.
J Thromb Haemost
. 2012 Jun;
10(8):1591-9.
PMID: 22726310
Background: Prophylaxis of hemophilia B, at present, requires multiple infusions of human factor (F)IX concentrates per week. A FIX molecule with a prolonged half-life has the potential to greatly improve...
4.
Nichols T, Franck H, Franck C, De Friess N, Raymer R, Merricks E
J Thromb Haemost
. 2012 Apr;
10(3):474-6.
PMID: 22482117
No abstract available.
5.
Karpf D, Kjalke M, Thim L, Agerso H, Merricks E, Defriess N, et al.
Haemophilia
. 2011 Jun;
17(5):e963-8.
PMID: 21682818
N8, a new recombinant factor VIII (rFVIII) compound developed for the treatment of haemophilia A, is produced in Chinese hamster ovary (CHO) cells and formulated without human- or animal-derived materials....
6.
Nichols T, Raymer R, Franck H, Merricks E, Bellinger D, Defriess N, et al.
Haemophilia
. 2010 Jul;
16 Suppl 3:19-23.
PMID: 20586797
Dogs with haemophilia A or haemophilia B exhibit spontaneous bleeding comparable with the spontaneous bleeding phenotype that occurs in humans with severe haemophilia. The phenotypic and genotypic characteristics of haemophilic...
7.
Ragni M, Jankowitz R, CHAPMAN H, Merricks E, Kloos M, Dillow A, et al.
Haemophilia
. 2008 Aug;
14(5):968-77.
PMID: 18680527
von Willebrand factor (VWF) is a multimeric glycoprotein that mediates platelet adhesion and is decreased in von Willebrand disease (VWD). 1-8 deamino-d-arginine vasopressin (DDAVP), the most common treatment for VWD,...
8.
Fischer T, Merricks E, Russell K, Raymer R, White G, Bode A, et al.
Br J Haematol
. 2000 Nov;
111(1):167-74.
PMID: 11091197
This study aimed to evaluate the effect of cross-linking and lyophilization on intracellular signalling processes in rehydrated, lyophilized (RL) platelets, which are under development as a platelet substitute for transfusion....
9.
Pryzwansky K, Merricks E
Mol Biol Cell
. 1998 Oct;
9(10):2933-47.
PMID: 9763453
In neutrophils activated to secrete with formyl-methionyl-leucyl-phenylalanine, intermediate filaments are phosphorylated transiently by cyclic guanosine monophosphate (cGMP)-dependent protein kinase (G-kinase). cGMP regulation of vimentin organization was investigated. During granule secretion,...
10.
Pryzwansky K, Kidao S, Merricks E
Cell Biochem Biophys
. 1998 Mar;
28(2-3):251-75.
PMID: 9515168
The compartmentalization of cAMP in human neutrophils during phagocytosis of serum-opsonized zymosan suggests that cAMP is an important second messenger for regulating phagocytosis. Type 4 cAMP-specific phosphodiesterase (PDE-4), cAMP-dependent protein...