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E Malta

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Articles 49
Citations 1507
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Recent Articles
1.
Ochs G, Penn R, York M, Giess R, Beck M, Tonn J, et al.
Amyotroph Lateral Scler Other Motor Neuron Disord . 2001 Jul; 1(3):201-6. PMID: 11464953
Background: Brain derived neurotrophic factor (BDNF) is a potent survival factor for motoneurons. This study investigated the safety and tolerability of recombinant methionyl human BDNF (r-metHuBDNF) infused intrathecally by means...
2.
Cedarbaum J, Stambler N, Malta E, Fuller C, Hilt D, Thurmond B, et al.
J Neurol Sci . 1999 Dec; 169(1-2):13-21. PMID: 10540002
The ALS Functional Rating Scale (ALSFRS) is a validated rating instrument for monitoring the progression of disability in patients with amyotrophic lateral sclerosis (ALS). One weakness of the ALSFRS as...
3.
Chello M, Mastroroberto P, Malta E, Cirillo F, Celi V
Ann Thorac Surg . 1999 Jun; 67(5):1277-82. PMID: 10355396
Background: Release of reactive oxygen radicals by activated neutrophils and neutrophil adhesion to endothelial cells have been observed after cardiopulmonary bypass. The aim of the present study was to evaluate...
4.
Malta E
Adv Neurol . 1995 Jan; 68:263-9; discussion 271-5. PMID: 8787239
These are but a few of the controversies and pressures facing Sponsors of clinical trials in ALS. All researchers in the area share the hope that the current level of...
5.
Morgan D, Richmond B, Malta E
Biopharm Drug Dispos . 1993 Oct; 14(7):627-33. PMID: 8251617
We investigated the effect of albumin (6%) on the (+/-)-isoprenaline-induced relaxation of strips of isolated rat uterus and its antagonism by (-)-propranolol. The mean isoprenaline EC50 in the presence of...
6.
Cocks T, Malta E, King S, Woods R, Angus J
Eur J Pharmacol . 1991 Apr; 196(2):177-82. PMID: 1874284
Cultured endothelial cells from bovine thoracic aortas conditioned with serum-free culture media released an endothelin-1 (ET)-1-like substance. Concentrations of ET-1-like material were determined by bioassay as contractions of isolated ring...
7.
Malta E
Clin Exp Pharmacol Physiol . 1989 Nov; 16(11):829-35. PMID: 2515014
1. The present study has examined the possibility that one or more metabolites of glyceryl trinitrate (GTN) (i.e. glyceryl-1,2- and -1,3-dinitrate and glyceryl-1- and -2-mononitrate) may be responsible for the...
8.
Ng N, Malta E
J Auton Pharmacol . 1989 Jun; 9(3):189-200. PMID: 2568361
1. The effects of the irreversible beta-adrenoreceptor antagonist bromoacetylalprenololmenthane (BAAM) were studied in isolated cardiac and uterine preparations from guinea-pigs and rats and in guinea-pig ileal preparations. 2. In the...
9.
Malta E
Naunyn Schmiedebergs Arch Pharmacol . 1989 Jan; 339(1-2):236-43. PMID: 2566926
The concentration-effect curve for the relaxant effects of glyceryl trinitrate (GTN) in rat aortic rings consisted of two phases with IC50 values of 0.1 microM for Phase I and 14...
10.
Malta E, Angus J
Clin Exp Pharmacol Physiol . 1988 Nov; 15(11):815-25. PMID: 3229006
1. The ability of P-286 (N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea) to reduce selectively the release of catecholamines from the adrenal medulla has been studied in urethane-anaesthetized rats. 2. Pressor responses to acetylcholine (Ach) and...