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E G Erdos

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Articles 186
Citations 2475
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Recent Articles
1.
Erdos E, Marcic B
Biol Chem . 2001 Mar; 382(1):43-7. PMID: 11258670
Based on studies presented here and other published experiments performed with surviving tissue preparations, with transfected cells and with cells that constitutively express the human angiotensin I converting enzyme ACE...
2.
Minshall R, Nedumgottil S, Igic R, Erdos E, Rabito S
Peptides . 2000 Oct; 21(8):1257-64. PMID: 11035213
Angiotensin I-converting enzyme (ACE/kininase II) inhibitors potentiated guinea pig ileum's isotonic contractions to bradykinin (BK) and its analogues, shifting the BK dose-response curve to the left. ACE inhibitors added at...
3.
Hecquet C, Tan F, Marcic B, Erdos E
Mol Pharmacol . 2000 Sep; 58(4):828-36. PMID: 10999954
Bradykinin (BK) and kallidin (Lys-BK), liberated from kininogens by kallikreins, are ligands of the BK B(2) receptor. We investigated whether kallikreins, besides releasing peptide agonist, could also activate the receptor...
4.
Marcic B, Deddish P, Jackman H, Erdos E, Tan F
Hypertension . 2000 Jul; 36(1):116-21. PMID: 10904022
Angiotensin I-converting enzyme (ACE, kininase II) has 2 active domains (N and C) in a single peptide chain. Because we found its N-domain more stable than its C-domain, we investigated...
5.
Marcic B, Erdos E
J Pharmacol Exp Ther . 2000 Jul; 294(2):605-12. PMID: 10900238
Angiotensin I-converting enzyme (kininase II) inhibitors (ACEis) are very widely used to treat cardiac conditions and nephropathies, but some of their beneficial activities cannot be attributed to enzyme inhibition alone....
6.
Marcic B, Deddish P, Skidgel R, Erdos E, Minshall R, Tan F
J Biol Chem . 2000 Apr; 275(21):16110-8. PMID: 10748135
To investigate further the relationship of angiotensin I-converting enzyme (ACE) inhibitors to activation of the B(2) bradykinin (BK) receptor, we transfected Chinese hamster ovary cells to stably express the human...
7.
Marcic B, Deddish P, Jackman H, Erdos E
Hypertension . 1999 Mar; 33(3):835-43. PMID: 10082496
We studied the enhancement of the effects of bradykinin B2 receptor agonists by agents that react with active centers of angiotensin-converting enzyme (ACE) independent of enzymatic inactivation. The potentiation and...
8.
Skidgel R, Erdos E
Immunol Rev . 1998 Apr; 161:129-41. PMID: 9553770
This article focuses on four human carboxypeptidases (CPs): two metallo-CPs and two serine CPs. The metallo-CPs are members of the so-called B-type regulatory CP family, as they cleave only the...
9.
Deddish P, Marcic B, Jackman H, Wang H, Skidgel R, Erdos E
Hypertension . 1998 Apr; 31(4):912-7. PMID: 9535414
We used the isolated N- and C-domains of the angiotensin 1-converting enzyme (N-ACE and C-ACE; ACE; kininase II) to investigate the hydrolysis of the active 1-7 derivative of angiotensin (Ang)...
10.
Dragovic T, Sekosan M, Becker R, Erdos E
Anticancer Res . 1997 Dec; 17(5A):3233-8. PMID: 9413153
Background: We have reported previously that neutral endopeptidase 24.11 (neprilysin; NEP; CALLA, CD10) activity was very high in rat hepatomas and a cultured human hepatocarcinoma cell line (SK-HEP1). Materials And...