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E E Slater

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Recent Articles
1.
Scolnick E, Slater E, Williams G
Adv Protein Chem . 2001 May; 56:1-12. PMID: 11329850
No abstract available.
2.
Slater E
Hypertension . 1991 Sep; 18(3 Suppl):I108-14. PMID: 1889851
While clinicians have long recognized the apparent increased prevalence of hypertension among diabetics, sophisticated epidemiological analyses begun in the early 1970s have established that hypertensive individuals are more prone to...
3.
Allard W, Vicario P, SAPERSTEIN R, Slater E, Strout H
Endocrinology . 1991 Jul; 129(1):169-75. PMID: 1905225
Adenylate cyclase activity was examined as a measure of inhibitory guanine nucleotide binding protein (Gi) function in liver plasma membranes from rats made chemically diabetic by streptozotocin (STZ) treatment. Clonidine...
4.
Brooks J, BERMAN C, Nguyen H, Prahalada S, Primka R, Rasmusson G, et al.
Prostate . 1991 Jan; 18(3):215-27. PMID: 1850515
Male rats bearing implants of the Dunning rat prostatic carcinoma, R-3327, were used in a 42-day study to determine the effect of castration or orally administered flutamide (FL), DES (diethylstilbestrol)...
5.
SAPERSTEIN R, CHAPIN E, BRADY E, Slater E
Metabolism . 1990 May; 39(5):445-51. PMID: 1970847
This study examines the effects of a relatively selective alpha 2-adrenoceptor antagonist, 8-(L-piperazinyl)imado-[1,2-alpha] pyrazine (compound A), and the preferential alpha 2-agonist clonidine on blood glucose, glucose tolerance, and plasma insulin...
6.
HARTMANN J, Chen S, Szemplinski M, Slater E
Horm Metab Res . 1990 Mar; 22(3):141-4. PMID: 2188897
Insulin therapy, administered by continuous subcutaneous infusion with osmotic pumps over a 28 day period at doses of 2.5 and 5.0 units/day, resulted in a statistically significant increase in body...
7.
Vicario P, Slater E, SAPERSTEIN R
Biochem Int . 1989 Sep; 19(3):553-61. PMID: 2510726
Sorbitol levels were determined in lens of genetically obese (ob/ob) and diabetic (db/db) mice, as well as in lean mice (+/db, +/ob) made diabetic by administration of streptozotocin (STZ). Treatment...
8.
SAPERSTEIN R, Vicario P, Strout H, Brady E, Slater E, Greenlee W, et al.
Biochemistry . 1989 Jun; 28(13):5694-701. PMID: 2550060
An inhibitor of the insulin receptor tyrosine kinase (IRTK), (hydroxy-2-naphthalenyl-methyl) phosphonic acid, was designed and synthesized and was shown to be an inhibitor of the biological effects of insulin in...
9.
Cascieri M, Slater E, Vicario P, Green B, Bayne M, SAPERSTEIN R
Diabetologia . 1989 Jun; 32(6):342-7. PMID: 2547681
The ability of insulin to modulate glucose metabolism is impaired in insulin resistant ob/ob mice. It has been shown that insulin-like growth factor I stimulates the uptake and metabolism of...
10.
Strout H, Vicario P, SAPERSTEIN R, Slater E
Endocrinology . 1989 Apr; 124(4):1918-24. PMID: 2647469
The in vivo administration of sodium orthovanadate stimulated the incorporation of [14C]glucose into [14C] glycogen, in a dose- and time-dependent manner, in mouse diaphragm. Activation of diaphragm insulin receptor was...