E E Baulieu
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Explore the profile of E E Baulieu including associated specialties, affiliations and a list of published articles.
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669
Citations
6243
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Recent Articles
1.
Akwa Y, Gondard E, Mann A, Capetillo-Zarate E, Alberdi E, Matute C, et al.
Mol Psychiatry
. 2017 Jul;
23(6):1530-1540.
PMID: 28696431
Changes in synaptic excitability and reduced brain metabolism are among the earliest detectable alterations associated with the development of Alzheimer's disease (AD). Stimulation of synaptic activity has been shown to...
2.
Kamah A, Cantrelle F, Huvent I, Giustiniani J, Guillemeau K, Byrne C, et al.
J Mol Biol
. 2016 Feb;
428(6):1080-1090.
PMID: 26903089
The aggregation of the neuronal Tau protein is one molecular hallmark of Alzheimer's disease and other related tauopathies, but the precise molecular mechanisms of the aggregation process remain unclear. The...
3.
Robel P, Baulieu E
Neurochem Int
. 2010 May;
7(6):953-8.
PMID: 20493007
Pregnenolone, dehydroepiandrosterone and their sulfate esters have been characterized in the rat brain. Their formation or accumulation depend on in situ mechanisms unrelated to the peripheral endocrine glands. Although their...
4.
Vukusic S, Ionescu I, El-Etr M, Schumacher M, Baulieu E, Cornu C, et al.
J Neurol Sci
. 2009 Sep;
286(1-2):114-8.
PMID: 19758607
Multiple sclerosis (MS) affects 1 in 1000 people in western countries, mainly women in their childbearing years. It is an autoimmune disease of the central nervous system, which results in...
5.
Goascogne C, Gouezou M, Robel P, Defaye G, Chambaz E, Waterman M, et al.
J Neuroendocrinol
. 2009 Feb;
1(3):153-6.
PMID: 19210447
Abstract Specific antibodies obtained in rabbits after injection of bovine cholesterol side-chain cleavage enzymes cytochrome P-450scc, adrenodoxin and adrenodoxin-reductase were used for immunohistochemical studies in human brain. The three enzymes...
6.
Dessouroux A, Akwa Y, Baulieu E
J Steroid Biochem Mol Biol
. 2008 Feb;
109(1-2):81-9.
PMID: 18261897
Previous work showed that dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary artery hypertension in rat via targeting smooth muscle cells. In our study, DHEA was tested on human pulmonary...
7.
Ghoumari A, Piochon C, Tomkiewicz C, Eychenne B, Levenes C, Dusart I, et al.
FASEB J
. 2006 Jul;
20(9):1377-86.
PMID: 16816113
In several regions of the developing nervous system, neurons undergo programmed cell death. In the rat cerebellum, Purkinje cell apoptosis is exacerbated when cerebellar slices are cultured during the first...
8.
Ghoumari A, Baulieu E, Schumacher M
Neuroscience
. 2005 Aug;
135(1):47-58.
PMID: 16054770
We have previously demonstrated that progesterone significantly increases the rate of myelination in organotypic slice cultures of 7-day-old rat and mouse cerebellum. Here, we show that progesterone (20microM) stimulates the...
9.
Schumacher M, Weill-Engerer S, Liere P, Robert F, Franklin R, Garcia-Segura L, et al.
Prog Neurobiol
. 2003 Nov;
71(1):3-29.
PMID: 14611864
Without medical progress, dementing diseases such as Alzheimer's disease will become one of the main causes of disability. Preventing or delaying them has thus become a real challenge for biomedical...
10.
Ghoumari A, Ibanez C, El-Etr M, Leclerc P, Eychenne B, OMalley B, et al.
J Neurochem
. 2003 Jul;
86(4):848-59.
PMID: 12887683
We have previously shown that progesterone (PROG) is synthesized by Schwann cells and promotes myelin formation in the peripheral nervous system (PNS). We now report that this neurosteroid also stimulates...