E C Hurt
Overview
Explore the profile of E C Hurt including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
3200
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Recent Articles
1.
The intracellular location of two aminoacyl-tRNA synthetases depends on complex formation with Arc1p
Galani K, Grosshans H, Deinert K, Hurt E, Simos G
EMBO J
. 2001 Dec;
20(23):6889-98.
PMID: 11726524
In yeast, two aminoacyl-tRNA synthetases, MetRS and GluRS, are associated with Arc1p. We have studied the mechanism of this complex formation and found that the non-catalytic N-terminally appended domains of...
2.
Deinert K, Fasiolo F, Hurt E, Simos G
J Biol Chem
. 2000 Nov;
276(8):6000-8.
PMID: 11069915
Eukaryotic aminoacyl-tRNA synthetases, in contrast to their prokaryotic counterparts, are often part of high molecular weight complexes. In yeast, two enzymes, the methionyl- and glutamyl-tRNA synthetases associate in vivo with...
3.
Fahrenkrog B, Aris J, Hurt E, Pante N, Aebi U
J Struct Biol
. 2000 May;
129(2-3):295-305.
PMID: 10806080
The nuclear pore complex (NPC) mediates protein and RNP import in and RNA and RNP export out of the nucleus of eukaryotic cells. Due to its genetic tractability, yeast offers...
4.
Siniossoglou S, Hurt E, Pelham H
J Biol Chem
. 2000 Apr;
275(25):19352-60.
PMID: 10777497
Regulation of intracellular ion concentration is an essential function of all cells. In this study, we report the identification of two previously uncharacterized genes, PSR1 and PSR2, that perform an...
5.
Rappsilber J, Siniossoglou S, Hurt E, Mann M
Anal Chem
. 2000 Feb;
72(2):267-75.
PMID: 10658319
Most cellular functions are performed by multi-protein complexes. The identity of the members of such complexes can now be determined by mass spectrometry. Here we show that mass spectrometry can...
6.
Massenet S, Motorin Y, Lafontaine D, Hurt E, Grosjean H, Branlant C
Mol Cell Biol
. 1999 Feb;
19(3):2142-54.
PMID: 10022901
Pseudouridine (Psi) residues were localized in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (UsnRNAs) by using the chemical mapping method. In contrast to vertebrate UsnRNAs, S. cerevisiae UsnRNAs contain...
7.
Fahrenkrog B, Hurt E, Aebi U, Pante N
J Cell Biol
. 1998 Nov;
143(3):577-88.
PMID: 9813081
The nuclear pore complex (NPC), a supramolecular assembly of approximately 100 different proteins (nucleoporins), mediates bidirectional transport of molecules between the cytoplasm and the cell nucleus. Extensive structural studies have...
8.
Kunzler M, Hurt E
FEBS Lett
. 1998 Sep;
433(3):185-90.
PMID: 9744791
CSE1 is essential for yeast cell viability and has been implicated in chromosome segregation. Based on its sequence similarity, Cse1p has been grouped into the family of importin beta-like nucleocytoplasmic...
9.
Simos G, Sauer A, Fasiolo F, Hurt E
Mol Cell
. 1998 Jul;
1(2):235-42.
PMID: 9659920
Two yeast enzymes that catalyze aminoacylation of tRNAs, MetRS and GluRS, form a complex with the protein Arc1p. We show here that association of Arc1p with MetRS and GluRS is...
10.
Lecointe F, Simos G, Sauer A, Hurt E, Motorin Y, Grosjean H
J Biol Chem
. 1998 Feb;
273(3):1316-23.
PMID: 9430663
The enzymatic activity of yeast gene product Deg1 was identified using both disrupted yeast strain and cloned recombinant protein expressed in yeast and in Escherichia coli. The results show that...