E C HENSHAW
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Explore the profile of E C HENSHAW including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
843
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Recent Articles
1.
Olmsted E, OBrien L, HENSHAW E, Panniers R
J Biol Chem
. 1993 Jun;
268(17):12552-9.
PMID: 8099583
A major mechanism of regulation of mammalian protein synthesis initiation is accomplished by the phosphorylation of the alpha subunit of eukaryotic initiation factor (eIF) 2. This modification inhibits the activity...
2.
Kumar R, Panniers R, Wolfman A, HENSHAW E
Eur J Biochem
. 1991 Jan;
195(2):313-9.
PMID: 1997317
Several recent publications indicate that Ca2+ is required for protein synthesis in mammalian cells, including the Ehrlich ascites tumor cell. The present communication examines whether the effects of Ca2+ might...
3.
Montine K, HENSHAW E
Biochem Biophys Res Commun
. 1990 Feb;
166(3):1340-5.
PMID: 2306245
Increased phosphorylation of ribosomal protein S6 has been extensively correlated with an increased rate of protein synthesis. We report here that under two separate conditions in Ehrlich cells an increase...
4.
Montine K, HENSHAW E
Biochim Biophys Acta
. 1989 Dec;
1014(3):282-8.
PMID: 2605256
In Ehrlich ascites tumor cells maintained in serum-free medium for 16 h the rate of protein synthesis was about 50% of the rate in control (well-fed) cells. The addition of...
5.
HENSHAW E, Bambara R
J Biol Chem
. 1989 Nov;
264(33):19478-86.
PMID: 2584181
The regulation of DNA polymerase alpha was examined in quiescent, human fibroblast cells stimulated to re-enter the cell cycle by subculturing in fresh serum-containing medium. The level of DNA polymerase...
6.
Kumar R, Wolfman A, Panniers R, HENSHAW E
J Cell Biol
. 1989 Jun;
108(6):2107-15.
PMID: 2500444
Protein synthesis in Ehrlich ascites tumor cells is inhibited when cellular calcium is depleted by the addition of EGTA to the growth medium. This inhibition is at the level of...
7.
Rowlands A, Montine K, HENSHAW E, Panniers R
Eur J Biochem
. 1988 Jul;
175(1):93-9.
PMID: 3402451
Previously, we have shown that phosphorylation of the eukaryotic initiation factor eIF-2 alpha increases under several physiological stresses in which protein synthesis is inhibited in Ehrlich ascites tumor cells. As...
8.
Rowlands A, Panniers R, HENSHAW E
J Biol Chem
. 1988 Apr;
263(12):5526-33.
PMID: 3356695
Guanine nucleotide exchange factor (GEF) is a multisubunit protein involved in the initiation of translation. Although numerous models have been proposed for its mechanism of action, none have been definitive....
9.
Panniers R, Rowlands A, HENSHAW E
J Biol Chem
. 1988 Apr;
263(12):5519-25.
PMID: 3356694
A major site of regulation of polypeptide chain initiation is the binding of Met-tRNA to 40 S ribosomal subunits which is mediated by eukaryotic initiation factor 2 (eIF-2). The formation...
10.
Scorsone K, Panniers R, Rowlands A, HENSHAW E
J Biol Chem
. 1987 Oct;
262(30):14538-43.
PMID: 3667588
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF-2) is a major mechanism regulating protein synthesis in rabbit reticulocytes. To determine whether phosphorylation of eIF-2 alpha is a...