E Bourinet
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Explore the profile of E Bourinet including associated specialties, affiliations and a list of published articles.
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28
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1159
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Recent Articles
1.
Libert F, Bonnefont J, Bourinet E, Doucet E, Alloui A, Hamon M, et al.
Mol Pharmacol
. 2004 Aug;
66(3):728-34.
PMID: 15322266
The reversal of the antinociceptive effect of systemically administered acetaminophen (paracetamol) by intrathecal administration of the potent 5-HT(3) receptor antagonist tropisetron has been reported in rats subjected to the paw...
2.
Bourinet E, Stotz S, Spaetgens R, Dayanithi G, Lemos J, Nargeot J, et al.
Biophys J
. 2001 Jun;
81(1):79-88.
PMID: 11423396
We have investigated the action of SNX482, a toxin isolated from the venom of the tarantula Hysterocrates gigas, on voltage-dependent calcium channels expressed in tsa-201 cells. Upon application of 200...
3.
Altier C, Spaetgens R, Nargeot J, Bourinet E, Zamponi G
Neuropharmacology
. 2001 Jun;
40(8):1050-7.
PMID: 11406197
Voltage- and frequency-dependent facilitation of calcium channel activity has been implicated in a number of key physiological processes. Various mechanisms have been proposed to mediate these regulations, including a switch...
4.
CHEMIN J, Monteil A, Bourinet E, Nargeot J, Lory P
Biophys J
. 2001 Feb;
80(3):1238-50.
PMID: 11222288
At least three genes encode T-type calcium channel alpha(1) subunits, and identification of cDNA transcripts provided evidence that molecular diversity of these channels can be further enhanced by alternative splicing...
5.
Feng Z, Hamid J, Doering C, Jarvis S, Bosey G, Bourinet E, et al.
J Biol Chem
. 2000 Dec;
276(8):5726-30.
PMID: 11120735
It is widely believed that the selectivity of voltage-dependent calcium channels is mainly controlled by amino acid residues contained within four p-loop motifs forming the pore of the channel. An...
6.
Leuranguer V, Monteil A, Bourinet E, Dayanithi G, Nargeot J
Am J Physiol Heart Circ Physiol
. 2000 Oct;
279(5):H2540-8.
PMID: 11045992
T-type Ca(2+) channels have been suggested to play a role in cardiac automaticity, cell growth, and cardiovascular remodeling. Although three genes encoding for a T-type Ca(2+) channel have been identified,...
7.
Lory P, Monteil A, CHEMIN J, Leuranguer V, Bourinet E, Nargeot J
Therapie
. 2000 Sep;
55(2):249-54.
PMID: 10967696
Voltage-gated calcium channels are involved in a large variety of cellular functions such as excitation-contraction coupling, hormone secretion, firing and pacemaker activity, gene activation and proliferation. Cloning of complementary DNAs...
8.
Monteil A, CHEMIN J, Leuranguer V, Altier C, Mennessier G, Bourinet E, et al.
J Biol Chem
. 2000 Apr;
275(22):16530-5.
PMID: 10749850
We have cloned and expressed a human alpha(1I) subunit that encodes a subtype of T-type calcium channels. The predicted protein is 95% homologous to its rat counterpart but has a...
9.
Monteil A, CHEMIN J, Bourinet E, Mennessier G, Lory P, Nargeot J
J Biol Chem
. 2000 Feb;
275(9):6090-100.
PMID: 10692398
We describe here several novel properties of the human alpha(1G) subunit that forms T-type calcium channels. The partial intron/exon structure of the corresponding gene CACNA1G was defined and several alpha(1G)...
10.
Jimenez C, Bourinet E, Leuranguer V, Richard S, Snutch T, Nargeot J
Neuropharmacology
. 2000 Feb;
39(1):1-10.
PMID: 10665814
The voltage gated calcium channel family is a major target for a range of therapeutic drugs. Mibefradil (Ro 40-5967) belongs to a new chemical class of these molecules which differs...