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E B Spector

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Articles 28
Citations 257
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1.
Bellus G, Spector E, Speiser P, Weaver C, GARBER A, Bryke C, et al.
Am J Hum Genet . 2000 Oct; 67(6):1411-21. PMID: 11055896
The fibroblast growth factor-receptor 3 (FGFR3) Lys650 codon is located within a critical region of the tyrosine kinase-domain activation loop. Two missense mutations in this codon are known to result...
2.
Spector E, Seltzer W, Goodman S
Mol Genet Metab . 1999 Aug; 67(4):364-7. PMID: 10444348
Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) is a nuclear-encoded protein located in the inner mitochondrial membrane. Inherited defects of ETF-QO cause glutaric acidemia type II. We here describe the localization of...
3.
Kruse C, Varella-Garcia M, Kleinschmidt-DeMasters B, Owens G, Spector E, Fakhrai H, et al.
In Vitro Cell Dev Biol Anim . 1998 Jul; 34(6):455-62. PMID: 9661048
Six human glioma cell lines were established from tissues obtained from five patients diagnosed with Kernohan grade IV glioblastoma multiforme and one from a patient with a grade II astrocytoma....
4.
Spector E, Jenkinson C, Grigor M, Kern R, Cederbaum S
Int J Dev Neurosci . 1994 Jun; 12(4):337-42. PMID: 7976488
Studies in man and other mammals have demonstrated the existence of two forms of arginase, a cytoplasmic form located primarily in liver and a mitochondrial form expressed in lesser amounts...
5.
Kruse C, Mitchell D, Kleinschmidt-DeMasters B, Franklin W, Morse H, Spector E, et al.
In Vitro Cell Dev Biol . 1992 Sep; 28A(9-10):609-14. PMID: 1331021
The establishment of a new glioma cell line, DBTRG-05MG, in a modified RPMI 1640 medium is described. The cells were derived from an adult female with glioblastoma multiforme who had...
6.
Boelter W, Burt B, Spector E, Hinton D, Pavlova Z, Fujimoto A
Prenat Diagn . 1990 Nov; 10(11):703-15. PMID: 1980950
A pregnant woman with indeterminate Duchenne muscular dystrophy (DMD) carrier status, but with DMD diagnosed in her deceased brother (unavailable for study), presented for prenatal diagnosis, intending to continue the...
7.
Grody W, Argyle C, Kern R, Dizikes G, Spector E, Strickland A, et al.
J Clin Invest . 1989 Feb; 83(2):602-9. PMID: 2913054
Previous studies in our laboratory and others have demonstrated in humans and other mammals two isozymes of arginase (AI and AII) that differ both electrophoretically and antigenically. AI, a cytosolic...
8.
Dizikes G, Spector E, Cederbaum S
Somat Cell Mol Genet . 1986 Jul; 12(4):375-84. PMID: 3461568
In order to study the regulation of expression of the two arginase genes in mammalian tissues, we undertook to clone cDNA specific for rat liver arginase. mRNA was isolated from...
9.
Spector E, Rice S, Kern R, Hendrickson R, Cederbaum S
Am J Hum Genet . 1985 Nov; 37(6):1138-45. PMID: 3936352
Arginase activity in red blood cells (RBC) of various mammalian species including man was determined. In nonprimate species, the activity generally fell below the level of detectability of the assay:...
10.
Spector E, Kern R, Haggerty D, Cederbaum S
Mol Cell Biochem . 1985 Feb; 66(1):45-53. PMID: 3920503
Arginase (EC 3.5.3.1), the final enzyme in the urea cycle, catalyzes the cleavage of arginine to orthinine and urea. At least two forms of this enzyme, AI and AII, have...