Dwight E Bergles
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Explore the profile of Dwight E Bergles including associated specialties, affiliations and a list of published articles.
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114
Citations
10477
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Recent Articles
1.
Duque M, Chen A, Hsu E, Narayan S, Rymbek A, Begum S, et al.
Neuron
. 2024 Dec;
113(3):426-443.e5.
PMID: 39694033
Transient exposure to ketamine can trigger lasting changes in behavior and mood. We found that brief ketamine exposure causes long-term suppression of futility-induced passivity in larval zebrafish, reversing the "giving-up"...
2.
Heo D, Kim A, Neumann B, Doze V, Xu Y, Mironova Y, et al.
bioRxiv
. 2024 Nov;
PMID: 39554158
Oligodendrocyte progenitor cells (OPCs) are highly dynamic, widely distributed glial cells of the central nervous system (CNS) that are responsible for generating myelinating oligodendrocytes during development. By also generating new...
3.
Hong I, Kim J, Hainmueller T, Kim D, Keijser J, Johnson R, et al.
Nature
. 2024 Oct;
635(8038):398-405.
PMID: 39358515
The brain helps us survive by forming internal representations of the external world. Excitatory cortical neurons are often precisely tuned to specific external stimuli. However, inhibitory neurons, such as parvalbumin-positive...
4.
Nguyen T, Bergles D
J Assoc Res Otolaryngol
. 2024 Jul;
25(5):525.
PMID: 39008230
No abstract available.
5.
Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction
Nguyen T, Bergles D
J Assoc Res Otolaryngol
. 2024 Jun;
25(5):409-412.
PMID: 38926267
Transient receptor potential (TRP) channels play key roles in sensory biology as transducers of various stimuli. Although these ion channels are expressed in the cochlea, their functions remain poorly understood....
6.
Foerster S, Floriddia E, van Bruggen D, Kukanja P, Herve B, Cheng S, et al.
Nat Neurosci
. 2024 Jun;
27(8):1545-1554.
PMID: 38849524
In the mouse embryonic forebrain, developmentally distinct oligodendrocyte progenitor cell populations and their progeny, oligodendrocytes, emerge from three distinct regions in a spatiotemporal gradient from ventral to dorsal. However, the...
7.
Kersbergen C, Bergles D
Trends Neurosci
. 2024 May;
47(7):522-537.
PMID: 38782701
Sensory systems experience a period of intrinsically generated neural activity before maturation is complete and sensory transduction occurs. Here we review evidence describing the mechanisms and functions of this 'spontaneous'...
8.
Kellner V, Parker P, Mi X, Yu G, Saher G, Bergles D
bioRxiv
. 2024 Apr;
PMID: 38659917
Afferent neurons in developing sensory organs exhibit a prolonged period of burst firing prior to the onset of sensory experience. This intrinsically generated activity propagates from the periphery through central...
9.
Gau Y, Hsu E, Cha R, Pak R, Looger L, Kang J, et al.
Nat Commun
. 2024 Apr;
15(1):3039.
PMID: 38589390
Astrocytes are a direct target of neuromodulators and can influence neuronal activity on broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our knowledge about...
10.
Looser Z, Faik Z, Ravotto L, Zanker H, Jung R, Werner H, et al.
Nat Neurosci
. 2024 Jan;
27(3):433-448.
PMID: 38267524
The integrity of myelinated axons relies on homeostatic support from oligodendrocytes (OLs). To determine how OLs detect axonal spiking and how rapid axon-OL metabolic coupling is regulated in the white...