Duygu Dee Harrison-Findik
Overview
Explore the profile of Duygu Dee Harrison-Findik including associated specialties, affiliations and a list of published articles.
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15
Citations
372
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Recent Articles
1.
Lu S, Bennett R, Kharbanda K, Harrison-Findik D
World J Hepatol
. 2016 Feb;
8(4):211-25.
PMID: 26855692
Aim: To investigate the role of key iron-regulatory protein, hepcidin in non-alcoholic fatty liver disease (NAFLD). Methods: Hepcidin (Hamp1) knockout and floxed control mice were administered a high fat and...
2.
Lu S, Natarajan S, Mott J, Kharbanda K, Harrison-Findik D
PLoS One
. 2016 Jan;
11(1):e0147474.
PMID: 26807955
Changes in lipid metabolism and iron content are observed in the livers of patients with fatty liver disease. The expression of hepcidin, an iron-regulatory and acute phase protein synthesized by...
3.
Lu S, Mott J, Harrison-Findik D
J Biol Chem
. 2015 Aug;
290(40):24178-89.
PMID: 26304124
Iron is implicated in fatty liver disease pathogenesis. The human hepcidin gene, HAMP, is the master switch of iron metabolism. The aim of this study is to investigate the regulation...
4.
Harrison-Findik D, Lu S
Biomolecules
. 2015 May;
5(2):793-807.
PMID: 25955433
This study investigates the regulation of hepcidin, the key iron-regulatory molecule, by alcohol and hydrogen peroxide (H2O2) in glutathione peroxidase-1 (gpx-1(-/-)) and catalase (catalase(-/-)) knockout mice. For alcohol studies, 10%...
5.
Zmijewski E, Lu S, Harrison-Findik D
World J Gastroenterol
. 2014 Sep;
20(34):12161-70.
PMID: 25232250
Aim: To understand the role of toll-like receptor 4 (TLR4) signaling in the regulation of iron-regulatory hormone, hepcidin by chronic alcohol consumption. Methods: For chronic alcohol intake studies, TLR4 mutant...
6.
Lu S, Zmijewski E, Gollan J, Harrison-Findik D
World J Biol Chem
. 2014 Sep;
5(3):387-97.
PMID: 25225605
Aim: To determine the regulation of human hepcidin (HAMP) and mouse hepcidin (hepcidin-1 and hepcidin-2) gene expression in the liver by apoptosis using in vivo and in vitro experimental models....
7.
Harrison-Findik D, Lu S, Zmijewski E, Jones J, Zimmerman M
World J Biol Chem
. 2013 Dec;
4(4):119-30.
PMID: 24340135
Aim: To understand the role of mitochondrial-produced superoxide (O2 (•-)) in the regulation of iron-regulatory hormone, hepcidin by alcohol in the liver. Methods: For alcohol experiments, manganese superoxide dismutase knockout...
8.
Lu S, Harrison-Findik D
World J Biol Chem
. 2013 Aug;
4(3):64-70.
PMID: 23977422
Autophagy is a homeostatic and evolutionarily conserved mechanism of self-digestion by which the cells degrade and recycle long-lived proteins and excess or damaged organelles. Autophagy is activated in response to...
9.
Gerjevic L, Lu S, Chaky J, Harrison-Findik D
World J Biol Chem
. 2012 Jan;
2(12):252-60.
PMID: 22216371
Aim: To study the effect of both acute and chronic alcohol exposure on heme oxygenases (HOs) in the brain, liver and duodenum. Methods: Wild-type C57BL/6 mice, heterozygous Sod2 knockout mice,...
10.
Gerjevic L, Liu N, Lu S, Harrison-Findik D
Int J Hepatol
. 2011 Nov;
2012:459278.
PMID: 22121494
Hepcidin, a key regulator of iron metabolism, is activated by bone morphogenetic proteins (BMPs). Mice pair-fed with regular and ethanol-containing L. De Carli diets were employed to study the effect...