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Duncan T Wilson

Explore the profile of Duncan T Wilson including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 15
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Recent Articles
1.
Wilson D, Hudson E, Brown S
BMC Med Res Methodol . 2024 Oct; 24(1):226. PMID: 39358754
Background: Whether or not to progress from a pilot study to a definitive trial is often guided by pre-specified quantitative progression criteria with three possible outcomes. Although the choice of...
2.
Wilson D, Brown J, Farrin A, Walwyn R
Stat Med . 2021 Jun; 40(21):4714-4731. PMID: 34121221
The power of a large clinical trial can be adversely affected by low recruitment, follow-up, and adherence rates. External pilot trials estimate these rates and use them, via prespecified decision...
3.
Wilson D, Wason J, Brown J, Farrin A, Walwyn R
Stat Med . 2021 Mar; 40(12):2877-2892. PMID: 33733500
External pilot trials of complex interventions are used to help determine if and how a confirmatory trial should be undertaken, providing estimates of parameters such as recruitment, retention, and adherence...
4.
Wilson D, Hooper R, Brown J, Farrin A, Walwyn R
Stat Methods Med Res . 2020 Dec; 30(3):799-815. PMID: 33267735
Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, however, restricted...
5.
Wilson D, Walwyn R, Brown J, Farrin A, Brown S
Stat Methods Med Res . 2015 Jun; 25(3):997-1009. PMID: 26071430
Early phase trials of complex interventions currently focus on assessing the feasibility of a large randomised control trial and on conducting pilot work. Assessing the efficacy of the proposed intervention...