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Amanda J Farrin

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Recent Articles
1.
Seymour V, Willis T, Weller A, Althaf M, Francis J, Lorencatto F, et al.
Health Informatics J . 2025 Mar; 31(1):14604582251317101. PMID: 40081406
Audit and feedback (A&F) programmes aim to improve patient care by providing summary data on performance to clinicians. They generally have modest, but variable, effects on patient care and questions...
2.
Moreau L, Ford A, Brookes M, Graca S, Guthrie E, Hartley S, et al.
Health Technol Assess . 2025 Mar; :1-30. PMID: 40079650
Background: Many patients with ulcerative colitis report ongoing diarrhoea even when their disease is stable and in remission. Design: MODULATE was a pragmatic, multicentre, seamless, adaptive, phase 2/3 open-label, parallel-group,...
3.
Wright-Hughes A, Farrin A, Fonagy P, Ougrin D, Stahl D, Wright J, et al.
J Am Acad Child Adolesc Psychiatry . 2025 Feb; PMID: 39892472
Objective: Self-harm is common in adolescents and a major public health concern. Evidence for effective interventions that stop repetition is lacking. This individual-participant-data (IPD) meta-analysis of randomised controlled trials (RCTs)...
4.
Wright-Hughes A, Ow P, Alderson S, Ridd M, Foy R, Bishop F, et al.
Gut . 2025 Jan; PMID: 39863398
Background: Low-dose amitriptyline, a tricyclic antidepressant (TCA), was superior to placebo for irritable bowel syndrome (IBS) in the AmitripTyline at Low-dose ANd Titrated for Irritable bowel syndrome as Second-line treatment...
5.
Green S, Graham C, Collinson M, Loo Ow P, Hall L, French D, et al.
Transl Behav Med . 2024 Dec; 15(1. PMID: 39657026
Adherence to adjuvant endocrine therapy in women with breast cancer is low. We conducted a 24-1 fractional factorial pilot optimization trial to test four intervention components supporting medication adherence [text...
6.
Pyne S, Sach T, Cameron R, Risebro H, Wright-Hughes A, Thompson E, et al.
Clin Rehabil . 2024 Dec; 39(2):161-173. PMID: 39639534
Objective: To compare costs and consequences of Early Stroke Specialist Vocational Rehabilitation (ESSVR) with usual care in working age, stroke survivors over 12 months. Design: An economic evaluation nested within...
7.
Wright-Hughes A, Ford A, Alderson S, Loo Ow P, Ridd M, Foy R, et al.
Health Technol Assess . 2024 Oct; 28(66):1-161. PMID: 39397570
Background: Irritable bowel syndrome, characterised by abdominal pain and a change in stool form or frequency, is most often managed in primary care. When first-line therapies are ineffective, National Institute...
8.
Clarke D, Powers K, Trusson D, Craven K, Phillips J, Holmes J, et al.
PLoS One . 2024 Oct; 19(10):e0311101. PMID: 39383146
Introduction: A key goal for working age stroke survivors is to return to work, yet only around 50% achieve this at 12 months. Currently, there is limited evidence of effectiveness...
9.
Teasdale E, Teasdale E, Everitt H, Everitt H, Alderson S, Alderson S, et al.
Br J Gen Pract . 2024 Aug; PMID: 39191441
Background: Irritable bowel syndrome (IBS) can cause troublesome symptoms, which impact patients' quality of life and incur considerable health service resource use. Guidelines suggest low-dose amitriptyline for IBS as second-line...
10.
Cragg W, Taylor C, Moreau L, Collier H, Gilberts R, McKigney N, et al.
Trials . 2024 May; 25(1):310. PMID: 38720375
Background: Use of electronic methods to support informed consent ('eConsent') is increasingly popular in clinical research. This commentary reports the approach taken to implement electronic consent methods and subsequent experiences...