Duane P Harland
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Explore the profile of Duane P Harland including associated specialties, affiliations and a list of published articles.
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34
Citations
171
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Recent Articles
1.
Baltenneck F, Genty G, Samra E, Richena M, Harland D, Clerens S, et al.
J Struct Biol
. 2022 Oct;
214(4):107908.
PMID: 36265530
Hair thinning occurs during normal chronological aging in women and in men leading to an increased level of thinner hair shafts alongside original thicker shafts. However, the characteristics of age-associated...
2.
Harland D, Popescu C, Richena M, Deb-Choudhury S, Wichlatz C, Lee E, et al.
Biophys J
. 2022 Apr;
121(11):2168-2179.
PMID: 35477858
Cysteine residues perform a dual role in mammalian hairs. The majority help stabilize the overall assembly of keratins and their associated proteins, but a proportion of inter-molecular disulfide bonds are...
3.
Plowman J, Harland D, Richena M, Thomas A, Hefer C, van Koten C, et al.
Proteins
. 2021 Dec;
90(4):973-981.
PMID: 34859500
Curvature in mammalian fibers, such as wool and human hair, is an important feature of the functional trait of coat structure-it affects mechanical resilience and thermo-insulation. However, to examine the...
4.
Plowman J, Miller R, Thomas A, Grosvenor A, Harland D, Deb-Choudhury S
Proteins
. 2021 Feb;
89(6):708-720.
PMID: 33550642
Trichocyte keratin intermediate filament proteins (keratins) and keratin associated proteins (KAPs) differ from their epithelial equivalents by having significantly more cysteine residues. Interactions between these cysteine residues within a mammalian...
5.
Plowman J, Harland D, Campos A, Rocha E Silva S, Thomas A, Vernon J, et al.
J Proteomics
. 2020 Jun;
225:103853.
PMID: 32534213
Wool properties and commodity value vary considerably between breeds. In Portugal, three major ovine groups exist: Churros, Bordaleiros and Merinos. This work studies the effect of the ovine genotype on...
6.
Plowman J, Harland D, Scobie D, OConnell D, Thomas A, Brorens P, et al.
Zoology (Jena)
. 2019 Apr;
133:40-53.
PMID: 30979389
Mammalian hairs are internally patterned from both a morphological and proteomic perspective to exhibit specific functional traits, including curvature, which is important for coat structure affecting thermo-insulation. Most functional traits...
7.
Harland D, Novotna V, Richena M, Velamoor S, Bostina M, McKinnon A
J Struct Biol
. 2019 Apr;
206(3):345-348.
PMID: 30965091
Macrofibrils, the main structural features within the cortical cells of mammalian hair shafts, are long composite bundles of keratin intermediate filaments (KIFs) embedded in a matrix of keratin-associated proteins. The...
8.
Lim Y, Harland D, Dawson Jr T
J Cosmet Sci
. 2019 Feb;
69(5):323-334.
PMID: 30767881
Research into biological manipulation of hair "quality" has ebbed and waned but today is in a resurgence. Hair appearance is regulated by multiple intervention opportunities-adding more hairs; increasing hair "amount"...
9.
Lim Y, Harland D, Dawson Jr T
Exp Dermatol
. 2019 Feb;
28(5):517-527.
PMID: 30706973
Human recorded history is littered with attempts to improve the perceived appearance of scalp hair. Throughout history, treatments have included both biological and chemical interventions. Hair "quality" or "perceived appearance"...
10.
Jakob E, Long S, Harland D, Jackson R, Carey A, Searles M, et al.
Curr Biol
. 2018 Sep;
28(18):R1092-R1093.
PMID: 30253146
One way of circumventing the functional tradeoffs on eye design [1,2] is to have different eyes for different tasks. For example, jumping spiders (Salticidae), known for elaborate, visually guided courtship...