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Druv Bhagavan

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Articles 7
Citations 29
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Recent Articles
1.
Guo J, Jiang H, Schuftan D, Moreno J, Ramahdita G, Aryan L, et al.
iScience . 2024 Jun; 27(6):109954. PMID: 38827401
Hypertension is a major cause of morbidity and mortality in patients with hypertrophic cardiomyopathy (HCM), suggesting a potential role for mechanics in HCM pathogenesis. Here, we developed an physiological model...
2.
Guo J, Jiang H, Schuftan D, Moreno J, Ramahdita G, Aryan L, et al.
bioRxiv . 2023 Nov; PMID: 37961198
Hypertrophic cardiomyopathy is the most common cause of sudden death in the young. Because the disease exhibits variable penetrance, there are likely nongenetic factors that contribute to the manifestation of...
3.
Oguntuyo K, Schuftan D, Guo J, Simmons D, Bhagavan D, Moreno J, et al.
Tissue Eng Part C Methods . 2022 Aug; 28(9):457-468. PMID: 35925789
Drugs are often removed from clinical trials or market progression owing to their unforeseen effects on cardiac action potential and calcium handling. Induced pluripotent stem cell-derived cardiomyocytes and tissues fabricated...
4.
Ransdell J, Moreno J, Bhagavan D, Silva J, Nerbonne J
Elife . 2022 Jan; 11. PMID: 35076394
The resurgent component of the voltage-gated sodium current (I) is a depolarizing conductance, revealed on membrane hyperpolarizations following brief depolarizing voltage steps, which has been shown to contribute to regulating...
5.
Moreno J, Bhagavan D, Li A, Gerstner N, Miller E, Huebsch N, et al.
Circ Heart Fail . 2021 Dec; 15(2):e008855. PMID: 34886677
No abstract available.
6.
Mangold K, Wang W, Johnson E, Bhagavan D, Moreno J, Nerbonne J, et al.
PLoS Comput Biol . 2021 Aug; 17(8):e1008932. PMID: 34398881
Markov models of ion channel dynamics have evolved as experimental advances have improved our understanding of channel function. Past studies have examined limited sets of various topologies for Markov models...
7.
Bhagavan D, Padovano W, Kovacs S
Am J Physiol Heart Circ Physiol . 2020 Mar; 318(5):H1059-H1067. PMID: 32142380
The spatiotemporal features of normal in vivo cardiac motion are well established. Longitudinal velocity has become a focus of diastolic function (DF) characterization, particularly the tissue Doppler -wave, manifesting in...