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Dries Decap

Explore the profile of Dries Decap including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 74
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Recent Articles
1.
Rahmani R, Decap D, Fostier J, Marchal K
DNA Res . 2022 Jul; 29(4). PMID: 35904558
With the decreasing cost of sequencing and availability of larger numbers of sequenced genomes, comparative genomics is becoming increasingly attractive to complement experimental techniques for the task of transcription factor...
2.
Decap D, de Schaetzen van Brienen L, Larmuseau M, Costanza P, Herzeel C, Wuyts R, et al.
Gigascience . 2022 Jan; 11(1). PMID: 35022699
Background: The accurate detection of somatic variants from sequencing data is of key importance for cancer treatment and research. Somatic variant calling requires a high sequencing depth of the tumor...
3.
Herzeel C, Costanza P, Decap D, Fostier J, Wuyts R, Verachtert W
PLoS One . 2021 Feb; 16(2):e0244471. PMID: 33539352
We present elPrep 5, which updates the elPrep framework for processing sequencing alignment/map files with variant calling. elPrep 5 can now execute the full pipeline described by the GATK Best...
4.
Perez-Romero C, Weytjens B, Decap D, Swings T, Michiels J, De Maeyer D, et al.
Nucleic Acids Res . 2019 May; 47(W1):W151-W157. PMID: 31127271
IAMBEE is a web server designed for the Identification of Adaptive Mutations in Bacterial Evolution Experiments (IAMBEE). Input data consist of genotype information obtained from independently evolved clonal populations or...
5.
Herzeel C, Costanza P, Decap D, Fostier J, Verachtert W
PLoS One . 2019 Feb; 14(2):e0209523. PMID: 30759172
We present elPrep 4, a reimplementation from scratch of the elPrep framework for processing sequence alignment map files in the Go programming language. elPrep 4 includes multiple new features allowing...
6.
Decap D, Reumers J, Herzeel C, Costanza P, Fostier J
PLoS One . 2017 Mar; 12(3):e0174575. PMID: 28358893
Given the current cost-effectiveness of next-generation sequencing, the amount of DNA-seq and RNA-seq data generated is ever increasing. One of the primary objectives of NGS experiments is calling genetic variants....
7.
De Witte D, Van de Velde J, Decap D, Van Bel M, Audenaert P, Demeester P, et al.
Bioinformatics . 2015 Aug; 31(23):3758-66. PMID: 26254488
Motivation: The accurate discovery and annotation of regulatory elements remains a challenging problem. The growing number of sequenced genomes creates new opportunities for comparative approaches to motif discovery. Putative binding...
8.
Herzeel C, Costanza P, Decap D, Fostier J, Reumers J
PLoS One . 2015 Jul; 10(7):e0132868. PMID: 26182406
elPrep is a high-performance tool for preparing sequence alignment/map files for variant calling in sequencing pipelines. It can be used as a replacement for SAMtools and Picard for preparation steps...
9.
Decap D, Reumers J, Herzeel C, Costanza P, Fostier J
Bioinformatics . 2015 Mar; 31(15):2482-8. PMID: 25819078
Motivation: Post-sequencing DNA analysis typically consists of read mapping followed by variant calling. Especially for whole genome sequencing, this computational step is very time-consuming, even when using multithreading on a...