Dovenia S Ponnoth
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Explore the profile of Dovenia S Ponnoth including associated specialties, affiliations and a list of published articles.
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14
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213
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Recent Articles
1.
Patel M, Narke D, Kurade M, Frey K, Rajalingam S, Siddiquee A, et al.
Purinergic Signal
. 2020 Aug;
16(3):415-426.
PMID: 32789792
Animal models of asthma have shown that limonene, a naturally occurring terpene in citrus fruits, can reduce inflammation and airway reactivity. However, the mechanism of these effects is unknown. We...
2.
Patel M, Kurade M, Rajalingam S, Bhavsar R, Mustafa S, Ponnoth D
Immunopharmacol Immunotoxicol
. 2019 May;
41(3):428-437.
PMID: 31062639
Angiotensin II (Ang II) exerts its effects through two G-protein coupled receptors: angiotensin II type 1 receptors (AT1) and type 2 receptors (AT2). Both these receptor subtypes are poorly understood...
3.
Siddiquee A, Patel M, Rajalingam S, Narke D, Kurade M, Ponnoth D
Immunopharmacol Immunotoxicol
. 2019 Mar;
41(2):250-257.
PMID: 30849257
ResolvinE1 (RvE1), an endogenous lipid mediator derived from omega 3 fatty acids contributes to resolution of allergic inflammatory responses. We investigated effects of RvE1 (R) and omega 3 fatty acids...
4.
Zaccone E, Thompson J, Ponnoth D, Cumpston A, Goldsmith W, Jackson M, et al.
J Toxicol Environ Health A
. 2013 Aug;
76(11):669-89.
PMID: 23941636
"Popcorn workers' lung" is an obstructive pulmonary disease produced by inhalation of volatile artificial butter flavorings. In rats, inhalation of diacetyl, a major component of butter flavoring, and inhalation of...
5.
Kunduri S, Mustafa S, Ponnoth D, Dick G, Nayeem M
J Cardiovasc Pharmacol
. 2013 Mar;
62(1):78-83.
PMID: 23519140
Adenosine A1 receptor (A1AR) activation contracts smooth muscle, although signaling mechanisms are not thoroughly understood. Activation of A1AR leads to metabolism of arachidonic acid, including the production of 20-hydroxyeicosatetraenoic acid...
6.
CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels
Ponnoth D, Nayeem M, Tilley S, Ledent C, Mustafa S
Am J Physiol Regul Integr Comp Physiol
. 2012 Sep;
303(10):R1003-10.
PMID: 23019210
Previously, we have shown that A(2A) adenosine receptor (A(2A)AR) mediates aortic relaxation via cytochrome P-450 (CYP)-epoxygenases. However, the signaling mechanism is not understood properly. We hypothesized that ATP-sensitive K(+) (K(ATP))...
7.
Ponnoth D, Nayeem M, Kunduri S, Tilley S, Zeldin D, Ledent C, et al.
Am J Physiol Regul Integr Comp Physiol
. 2011 Dec;
302(4):R400-8.
PMID: 22160543
Previously, we have shown that A(2A) adenosine receptor (A(2A)AR) knockout mice (KO) have increased contraction to adenosine. The signaling mechanism(s) for A(2A)AR is still not fully understood. In this study,...
8.
Ponnoth D, Mustafa S
Biochim Biophys Acta
. 2010 Sep;
1808(5):1429-34.
PMID: 20832387
Epidemiological studies have shown a positive correlation between poor lung function and respiratory disorders like asthma and the development of adverse cardiovascular events. Increased adenosine (AD) levels are associated with...
9.
Nayeem M, Zeldin D, Boegehold M, Morisseau C, Marowsky A, Ponnoth D, et al.
Am J Physiol Regul Integr Comp Physiol
. 2010 Apr;
299(1):R325-33.
PMID: 20427718
High-salt intake can change the effect of adenosine on arterial tone in mice. The aim of this study was to clarify the mechanism by which this occurs. Using aortas from...
10.
Ponnoth D, Nadeem A, Tilley S, Mustafa S
Am J Physiol Heart Circ Physiol
. 2010 Apr;
299(1):H81-7.
PMID: 20400685
Poor lung function and respiratory disorders like asthma have a positive correlation with the development of adverse cardiovascular events. Increased adenosine levels are associated with lung inflammation that could lead...