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Douglas J Watson

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Articles 35
Citations 627
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Recent Articles
11.
Cui Y, Watson D, Girman C, Shapiro D, Gotto A, Hiserote P, et al.
Am J Cardiol . 2009 Sep; 104(6):829-34. PMID: 19733719
Reducing low-density lipoprotein (LDL) cholesterol with statins reduces cardiovascular risk, but the associations between increases in high-density lipoprotein (HDL) cholesterol and cardiovascular risk at different LDL levels have been less...
12.
Schlesinger N, Norquist J, Watson D
J Rheumatol . 2009 Apr; 36(6):1287-9. PMID: 19369457
Objective: To study the frequency of normal serum urate (SU) levels during acute gout in the largest studies of acute gout treatment to date. Methods: Data collected from 2 randomized...
13.
Kamal-Bahl S, Watson D, Ambegaonkar B
Clin Ther . 2009 Feb; 31(1):130-40. PMID: 19243714
Background: Niacin is highly effective at raising high-density lipoprotein cholesterol but remains underused because of the adverse event of flushing. Objective: The objective of this study was to determine the...
14.
Kamal-Bahl S, Burke T, Watson D, Wentworth C
Curr Med Res Opin . 2008 May; 24(6):1817-21. PMID: 18485268
Objective: To examine the dosage, titration patterns, and gaps in treatment of newly-initiated ER niacin in clinical practice. Research Design And Methods: Historical cohort study using the Ingenix Lab/Rx database....
15.
Avins A, Manos M, Ackerson L, Zhao W, Murphy R, Levin T, et al.
Drug Saf . 2008 Mar; 31(4):325-34. PMID: 18366243
Background: Little is known about the potential adverse hepatic effects of HMG-CoA reductase inhibitors ('statins') in patients with existing liver disease; therefore, we examined the risk of liver toxicity with...
16.
Paolini J, Mitchel Y, Reyes R, Kher U, Lai E, Watson D, et al.
Am J Cardiol . 2008 Mar; 101(5):625-30. PMID: 18308010
Niacin (nicotinic acid) is not optimally used mainly because of flushing, a process mediated primarily by prostaglandin D(2), which leads to poor patient compliance and suboptimal dosing. This phase II...
17.
Morrison A, Ramey D, van Adelsberg J, Watson D
Curr Med Res Opin . 2007 Aug; 23(10):2395-404. PMID: 17714606
Objective: To investigate the effects of continued use of non-selective NSAIDs (nsNSAIDs) on blood pressure and hypertension. Research Design And Methods: This was a systematic review of randomized clinical trials...
18.
Norquist J, Watson D, Yu Q, Paolini J, McQuarrie K, Santanello N
Curr Med Res Opin . 2007 Jun; 23(7):1549-60. PMID: 17559750
Background: Niacin is currently the most effective approved agent for raising high-density lipoprotein cholesterol. However, niacin-induced cutaneous flushing (redness, warmth, tingling and/or itching) significantly limits patient acceptance. To further characterize...
19.
Watson D, Rahme E, Santanello N
Drug Saf . 2006 Dec; 30(1):89-90. PMID: 17194174
No abstract available.
20.
Rahme E, Watson D, Kong S, Toubouti Y, LeLorier J
Pharmacoepidemiol Drug Saf . 2006 Nov; 16(5):493-503. PMID: 17086567
Purpose: To evaluate the association between rofecoxib, celecoxib, diclofenac, and ibuprofen and the risk of hospitalization for acute myocardial infarction (AMI) in an elderly population. Methods: We conducted a retrospective...