James A Bolognese
Overview
Explore the profile of James A Bolognese including associated specialties, affiliations and a list of published articles.
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21
Citations
1154
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Recent Articles
1.
Bolognese J, Subach R, Skobieranda F
Ther Innov Regul Sci
. 2018 Sep;
49(5):756-766.
PMID: 30227035
Background: Conventional opioids provide powerful analgesia but also produce efficacy-limiting adverse effects, limiting their clinical utility (CU). TRV130 is being evaluated to determine whether CU can be expanded by way...
2.
Viscusi E, Webster L, Kuss M, Daniels S, Bolognese J, Zuckerman S, et al.
Pain
. 2015 Dec;
157(1):264-272.
PMID: 26683109
Efficacy of conventional opioids can be limited by adverse events (AEs). TRV130 is a structurally novel biased ligand of the μ-opioid receptor that activates G protein signaling with little β-arrestin...
3.
Seymour M, Kelly S, Beals C, Malice M, Bolognese J, Dardzinski B, et al.
Arthritis Res Ther
. 2012 Sep;
14(5):R198.
PMID: 22972032
Introduction: We aimed to investigate the sensitivity and reliability of two-dimensional ultrasonographic endpoints at the metacarpophalageal joints (MCPJs) and their potential to provide an early and objective indication of a...
4.
Gammaitoni A, Smugar S, Jensen M, Galer B, Bolognese J, Alon A, et al.
Pain Med
. 2012 Jul;
14(4):526-32.
PMID: 22759088
Objective: The aim of this study is to assess the Pain Quality Assessment Scale (PQAS) in predicting pregabalin in peripheral neuropathic pain (NP). Study Design: Post hoc analysis of a...
5.
Schoeller D, Alon A, Manekas D, Mixson L, Lasseter K, Noonan G, et al.
Clin Ther
. 2012 Mar;
34(3):580-92.
PMID: 22385927
Background: The development of antihypertensives requires efficient and accurate tools for identifying pedal edema. Methodologies used to gauge the potential of an agent to induce pedal edema in short-term (<4-week)...
6.
Myers K, Rudd J, Hailman E, Bolognese J, Burke J, Pinto C, et al.
JACC Cardiovasc Imaging
. 2012 Jan;
5(1):38-45.
PMID: 22239891
Objectives: A prospective, multicenter (18)fluorine-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging study was performed to estimate the correlations among arterial FDG uptake and atherosclerotic plaque biomarkers in patients...
7.
Jensen M, Gammaitoni A, Bolognese J, Alon A, Smugar S, Galer B, et al.
Clin J Pain
. 2011 Dec;
28(8):683-6.
PMID: 22156827
Objective: To identify and describe the response profile of pregabalin on the qualities of pain associated with peripheral neuropathy. Methods: A post hoc analysis to examine the effects of pregabalin...
8.
Chen F, Maridakis V, ONeill E, Beals C, Radziszewski W, De Lepeleire I, et al.
Platelets
. 2011 Sep;
23(4):249-58.
PMID: 21919555
Traditional assays of the coagulation status of patients, bleeding time assessment (BT) and light transmission aggregometry (LTA), are useful in clinical drug development. However, these assays are both labor intensive...
9.
Kaufman R, Nunes I, Bolognese J, Miller D, Salotti D, McCarthy J, et al.
J Am Soc Hypertens
. 2010 Dec;
4(6):311-8.
PMID: 21130977
Antihypertensive drugs can have different effects on central and brachial blood pressures, which may affect outcomes. Nitric oxide donors have acute effects on central blood pressure but have not been...
10.
Perlstein I, Bolognese J, Krishna R, Wagner J
AAPS J
. 2009 Sep;
11(4):653-63.
PMID: 19763840
The aim of the investigation was to evaluate alternatives to standard first-in-human (FIH) designs in order to optimize the information gained from such studies by employing novel agile trial designs....