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Doug Holmyard

Explore the profile of Doug Holmyard including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 317
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Recent Articles
1.
Mulcahy B, Witvliet D, Mitchell J, Schalek R, Berger D, Wu Y, et al.
Curr Biol . 2022 Oct; 32(21):4645-4659.e3. PMID: 36283410
During development, animals can maintain behavioral output even as underlying circuitry structurally remodels. After hatching, C. elegans undergoes substantial motor neuron expansion and synapse rewiring while the animal continuously moves...
2.
Lant B, Yu B, Goudreault M, Holmyard D, Knight J, Xu P, et al.
Nat Commun . 2015 Mar; 6:6449. PMID: 25743393
The mechanisms governing apical membrane assembly during biological tube development are poorly understood. Here, we show that extension of the C. elegans excretory canal requires cerebral cavernous malformation 3 (CCM-3),...
3.
Waters A, Wu M, Huang Y, Liu G, Holmyard D, Onay T, et al.
J Am Soc Nephrol . 2011 Nov; 23(1):27-35. PMID: 22052054
Notch signaling in podocytes causes proteinuria and glomerulosclerosis in humans and rodents, but the underlying mechanism remains unknown. Here, we analyzed morphologic, molecular, and cellular events before the onset of...
4.
Adamson S, Lu Y, Whiteley K, Holmyard D, Hemberger M, Pfarrer C, et al.
Dev Biol . 2002 Oct; 250(2):358-73. PMID: 12376109
Mammalian embryos have an intimate relationship with their mothers, particularly with the placental vasculature from which embryos obtain nutrients essential for growth. It is an interesting vascular bed because maternal...
5.
Kimura Y, Hart A, Hirashima M, Wang C, Holmyard D, Pittman J, et al.
J Exp Med . 2002 Apr; 195(7):941-52. PMID: 11927637
Using an expression gene trapping strategy, we recently identified a novel gene, hematopoietic zinc finger (Hzf), which encodes a protein containing three C(2)H(2)-type zinc fingers that is predominantly expressed in...