Doug Brooks
Overview
Explore the profile of Doug Brooks including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
212
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0
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Recent Articles
1.
Lewis F, Beirne J, Henderson B, Norris L, Cadoo K, Kelly T, et al.
Cancer Lett
. 2024 Sep;
605:217279.
PMID: 39341451
Epithelial ovarian carcinoma (EOC) is the eighth most common cancer in women and the leading cause of gynaecological cancer death, predominantly due to the absence of effective screening tools, advanced...
2.
Bates M, Mohamed B, Ward M, Kelly T, OConnor R, Malone V, et al.
Biochim Biophys Acta Rev Cancer
. 2023 Feb;
1878(2):188863.
PMID: 36796527
This review is an overview of the current knowledge regarding circulating tumour cells (CTCs), which are potentially the most lethal type of cancer cell, and may be a key component...
3.
Lazniewska J, Bader C, Hickey S, Selemidis S, OLeary J, Simpson P, et al.
Metallomics
. 2022 Jun;
14(8).
PMID: 35657681
Cholesterol is vital to control membrane integrity and fluidity, but is also a precursor to produce steroid hormones, bile acids, and vitamin D. Consequently, altered cholesterol biology has been linked...
4.
Bates M, Spillane C, Gallagher M, McCann A, Martin C, Blackshields G, et al.
PLoS One
. 2020 Dec;
15(12):e0243715.
PMID: 33370338
Despite the use of front-line anticancer drugs such as paclitaxel for ovarian cancer treatment, mortality rates have remained almost unchanged for the past three decades and the majority of patients...
5.
Brooks D, Olver I, Esterman A
Med J Aust
. 2018 Jun;
208(10):426-427.
PMID: 29848243
No abstract available.
6.
Lock M, Botting K, Tellam R, Brooks D, Morrison J
Int J Mol Sci
. 2017 Dec;
18(12).
PMID: 29210999
Placental insufficiency, high altitude pregnancies, maternal obesity/diabetes, maternal undernutrition and stress can result in a poor setting for growth of the developing fetus. These adverse intrauterine environments result in physiological...
7.
He X, Pierce O, Haselhorst T, von Itzstein M, Kolarich D, Packer N, et al.
Plant Biotechnol J
. 2013 Aug;
11(9):1034-43.
PMID: 23898885
Mucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this genetic disease. Arabidopsis cgl...
8.
Keep S, Borlace G, Butler R, Brooks D
Helicobacter
. 2010 Jun;
15(3):177-83.
PMID: 20557358
Background: Helicobacter pylori infection can lead to the development of gastritis, peptic ulcers and gastric cancer, which makes this bacterium an important concern for human health. Despite evoking a strong...
9.
Tarpey P, Raymond F, Nguyen L, Rodriguez J, Hackett A, Vandeleur L, et al.
Nat Genet
. 2007 Aug;
39(9):1127-33.
PMID: 17704778
Nonsense-mediated mRNA decay (NMD) is of universal biological significance. It has emerged as an important global RNA, DNA and translation regulatory pathway. By systematically sequencing 737 genes (annotated in the...
10.
Parkinson-Lawrence E, Turner C, Hopwood J, Brooks D
Biochem J
. 2004 Oct;
386(Pt 2):395-400.
PMID: 15500445
Mammalian sulphatases (EC 3.1.6) are a family of enzymes that have a high degree of similarity in amino acid sequence, structure and catalytic mechanism. IDS (iduronate-2-sulphatase; EC 3.1.6.13) is a...