Dorsaf Ghalloussi
Overview
Explore the profile of Dorsaf Ghalloussi including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
255
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Recent Articles
1.
Lee R, Ghalloussi D, Harousseau G, Kenny J, Kramer P, Proamer F, et al.
JCI Insight
. 2022 Mar;
7(8).
PMID: 35290242
Platelet homeostasis is dependent on a tight regulation of both platelet production and clearance. The small GTPase Rap1 mediates platelet adhesion and hemostatic plug formation. However, Rap1 signaling is also...
2.
Eckly A, Scandola C, Oprescu A, Michel D, Rinckel J, Proamer F, et al.
J Thromb Haemost
. 2020 Jul;
18(11):2987-3001.
PMID: 32702204
Background: Blood platelets are anucleate cell fragments that prevent bleeding and minimize blood vessel injury. They are formed from the cytoplasm of megakaryocytes located in the bone marrow. For successful...
3.
Ghalloussi D, Rousset-Rouviere C, Popovici C, Garaix F, Saut N, Saultier P, et al.
Br J Haematol
. 2020 Feb;
188(6):e87-e90.
PMID: 32030720
No abstract available.
4.
Ghalloussi D, Dhenge A, Bergmeier W
J Thromb Haemost
. 2019 Jun;
17(9):1430-1439.
PMID: 31220402
The past decade has brought unprecedented advances in our understanding of megakaryocyte (MK) biology and platelet production, processes that are strongly dependent on the cytoskeleton. Facilitated by technological innovations, such...
5.
Stefanini L, Lee R, Paul D, OShaughnessy E, Ghalloussi D, Jones C, et al.
Blood
. 2018 Aug;
132(18):1951-1962.
PMID: 30131434
RAP GTPases, important regulators of cellular adhesion, are abundant signaling molecules in the platelet/megakaryocytic lineage. However, mice lacking the predominant isoform, RAP1B, display a partial platelet integrin activation defect and...
6.
Paul D, Casari C, Wu C, Piatt R, Pasala S, Campbell R, et al.
Blood Adv
. 2017 Nov;
1(18):1398-1408.
PMID: 29104956
Actin reorganization regulates key processes in platelet activation. Here we examined the role of the Arp2/3 complex, an essential component in actin filament branching, in platelet function. The gene, encoding...
7.
Ghalloussi D, Saut N, Bernot D, Pillois X, Rameau P, Sebahoun G, et al.
Br J Haematol
. 2017 Oct;
183(3):503-506.
PMID: 29082515
No abstract available.
8.
Poggi M, Canault M, Favier M, Turro E, Saultier P, Ghalloussi D, et al.
Haematologica
. 2016 Sep;
102(2):282-294.
PMID: 27663637
Variants in ETV6, which encodes a transcription repressor of the E26 transformation-specific family, have recently been reported to be responsible for inherited thrombocytopenia and hematologic malignancy. We sequenced the DNA...
9.
Canault M, Ghalloussi D, Grosdidier C, Guinier M, Perret C, Chelghoum N, et al.
J Exp Med
. 2014 Jun;
211(7):1349-62.
PMID: 24958846
The nature of an inherited platelet disorder was investigated in three siblings affected by severe bleeding. Using whole-exome sequencing, we identified the culprit mutation (cG742T) in the RAS guanyl-releasing protein-2...
10.
Noris P, Favier R, Alessi M, Geddis A, Kunishima S, Heller P, et al.
Blood
. 2013 Sep;
122(11):1987-9.
PMID: 24030261
No abstract available.