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Doris Benbrook

Explore the profile of Doris Benbrook including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 127
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Recent Articles
1.
Csiszar A, Balasubramanian P, Tarantini S, Yabluchanskiy A, Zhang X, Springo Z, et al.
Geroscience . 2019 May; 41(2):209-227. PMID: 31037472
There is significant overlap between the cellular and molecular mechanisms of aging and pathways contributing to carcinogenesis, including the role of genome maintenance pathways. In the field of geroscience analysis...
2.
Palwai N, Zang X, Harrison R, Benbrook D, Pento J
Pharmacology . 2009 Oct; 84(5):271-5. PMID: 19797936
Background: We have reported the development of a novel fusion protein (FP) consisting of an amino-terminal fragment of urokinase linked to the amino terminus of the enzyme L-methioninase (L-M). The...
3.
McMeekin D, Sill M, Darcy K, Stearns-Kurosawa D, Webster K, Waggoner S, et al.
Gynecol Oncol . 2007 Jun; 106(3):596-603. PMID: 17597196
Objectives: To evaluate the efficacy and adverse events (AEs) of thalidomide in previously treated, measurable, persistent or recurrent leiomyosarcoma (LMS) of the uterus, and to explore associations between angiogenic markers...
4.
Liu T, Hannafon B, Gill L, Kelly W, Benbrook D
Mol Cancer Ther . 2007 Jun; 6(6):1814-22. PMID: 17575110
Flex-Het drugs induce apoptosis in multiple types of cancer cells, with little effect on normal cells. This apoptosis occurs through the intrinsic mitochondrial pathway accompanied by generation of reactive oxygen...
5.
McMeekin D, Sill M, Benbrook D, Darcy K, Stearns-Kurosawa D, Eaton L, et al.
Gynecol Oncol . 2007 Feb; 105(2):508-16. PMID: 17306350
Objectives: A phase II trial was conducted to evaluate the anti-tumor activity and adverse effects of thalidomide in persistent or recurrent endometrial cancer refractory to cytotoxic chemotherapy and to correlate...
6.
Hassan R, Lerner M, Benbrook D, Lightfoot S, Brackett D, Wang Q, et al.
Clin Cancer Res . 2002 Nov; 8(11):3520-6. PMID: 12429643
Purpose: Mesothelin, a cell surface glycoprotein overexpressed in ovarian cancer, mesotheliomas, and some squamous cell carcinomas, is an attractive candidate for targeted therapy because it is not shed in significant...