Doreen Biedenweg
Overview
Explore the profile of Doreen Biedenweg including associated specialties, affiliations and a list of published articles.
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15
Citations
147
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Recent Articles
1.
Fregin B, Hossain M, Biedenweg D, Friedrichs V, Balkema-Buschmann A, Bokelmann M, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(43):e2405169121.
PMID: 39401351
Hibernation is a widespread and highly efficient mechanism to save energy in mammals. However, one major challenge of hibernation is maintaining blood circulation at low body temperatures, which strongly depends...
2.
Wittmann N, Bekeschus S, Biedenweg D, Kuthning D, Pohl C, Gramenz J, et al.
Inflammation
. 2024 Sep;
PMID: 39256305
Inflammasome activation occurs in various diseases, including rare diseases that require multicenter studies for investigation. Flow cytometric analysis of ASC speck cells in patient samples can be used to detect...
3.
Redwanz C, Pires R, Biedenweg D, Gross S, Otto O, Konemann S
J Mol Cell Cardiol
. 2024 Jul;
194:105-117.
PMID: 39019395
A better understanding of the underlying pathomechanisms of diastolic dysfunction is crucial for the development of targeted therapeutic options with the aim to increase the patients' quality of life. In...
4.
Yanamandra A, Zhang J, Montalvo G, Zhou X, Biedenweg D, Zhao R, et al.
Eur J Immunol
. 2024 Jan;
54(3):e2350693.
PMID: 38279603
Natural killer (NK) cells play a vital role in eliminating tumorigenic cells. Efficient locating and killing of target cells in complex three-dimensional (3D) environments are critical for their functions under...
5.
Sampietro M, Cassina V, Salerno D, Barbaglio F, Buglione E, Marrano C, et al.
Hemasphere
. 2023 Jul;
7(8):e931.
PMID: 37492437
Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by an intense trafficking of the leukemic cells between the peripheral blood and lymphoid tissues. It is known that the ability...
6.
Dabbiru V, Manu E, Biedenweg D, Nestler P, Pires R, Otto O
Cytoskeleton (Hoboken)
. 2022 Oct;
80(1-2):21-33.
PMID: 36310101
Alterations in the organization of the cytoskeleton precede the escape of adherent cells from the framework of cell-cell and cell-matrix interactions into suspension. With cytoskeletal dynamics being linked to cell...
7.
Wilden A, Glaubitz J, Otto O, Biedenweg D, Nauck M, Mack M, et al.
Front Immunol
. 2022 Oct;
13:991295.
PMID: 36300116
Objective: Acute pancreatitis (AP) is an inflammatory disorder, the severe form of which is burdened with multi-organ dysfunction and high mortality. The pathogenesis of life -threatening organ complications, such as...
8.
Rath M, Schwefel K, Malinverno M, Skowronek D, Leopoldi A, Pilz R, et al.
Cell Mol Life Sci
. 2022 Jun;
79(6):340.
PMID: 35661927
Cerebral cavernous malformations (CCM) are low-flow vascular lesions prone to cause severe hemorrhage-associated neurological complications. Pathogenic germline variants in CCM1, CCM2, or CCM3 can be identified in nearly 100% of...
9.
Fregin B, Biedenweg D, Otto O
Biomicrofluidics
. 2022 May;
16(2):024109.
PMID: 35541026
The capability to parameterize shapes is of essential importance in biomechanics to identify cells, to track their motion, and to quantify deformation. While various shape descriptors have already been investigated...
10.
Busch K, Kny M, Huang N, Klassert T, Stock M, Hahn A, et al.
J Cachexia Sarcopenia Muscle
. 2021 Sep;
12(6):1653-1668.
PMID: 34472725
Background: Septic cardiomyopathy worsens the prognosis of critically ill patients. Clinical data suggest that interleukin-1β (IL-1β), activated by the NLRP3 inflammasome, compromises cardiac function. Whether or not deleting Nlrp3 would...