Doraiswami Ramkrishna
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Explore the profile of Doraiswami Ramkrishna including associated specialties, affiliations and a list of published articles.
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51
Citations
358
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Recent Articles
1.
Khanum S, Gupta S, Maurya M, Raja R, Aboulmouna L, Subramaniam S, et al.
J Lipid Res
. 2024 Oct;
65(12):100666.
PMID: 39395792
Cellular metabolism is a complex process involving the consumption and production of metabolites, as well as the regulation of enzyme synthesis and activity. Modeling of metabolic processes is important to...
2.
Curtis G, Ramkrishna D, Narsimhan V
Phys Rev E
. 2024 Sep;
110(2-1):024131.
PMID: 39295004
We examine continuous random walks that are conditioned to reach one region before another. These conditioned processes are used to generate stochastic trajectories for barrier crossing events, which are generally...
3.
Raja R, Khanum S, Aboulmouna L, Maurya M, Gupta S, Subramaniam S, et al.
Biophys J
. 2023 Dec;
123(2):221-234.
PMID: 38102827
Quantitative understanding of cellular processes, such as cell cycle and differentiation, is impeded by various forms of complexity ranging from myriad molecular players and their multilevel regulatory interactions, cellular evolution...
4.
Pandey A, Raja R, Estepp J, Ramkrishna D
CPT Pharmacometrics Syst Pharmacol
. 2023 May;
12(6):748-757.
PMID: 37194405
Nonadherence is common in individuals with sickle cell disease (SCD) on hydroxyurea therapy and can be observed with waning improvements in hematologic parameters or biomarkers like mean cell volume and...
5.
Bulutoglu P, Zalte A, Nere N, Ramkrishna D, Corti D
J Chem Phys
. 2023 Apr;
158(13):134505.
PMID: 37031149
Computational predictions of the polymorphic outcomes of a crystallization process, referred to as polymorph selection, can accelerate the process development for manufacturing solid products with targeted properties. Polymorph selection requires...
6.
Raja R, Khanum S, Aboulmouna L, Maurya M, Gupta S, Subramaniam S, et al.
bioRxiv
. 2023 Mar;
PMID: 36993235
Statement Of Significance: Cellular processes like cell cycle are overly complex, involving multiple players interacting at multiple levels, and explicit modeling of such systems is challenging. The availability of longitudinal...
7.
Bulutoglu P, Wang S, Boukerche M, Nere N, Corti D, Ramkrishna D
PNAS Nexus
. 2023 Jan;
1(2):pgac033.
PMID: 36713321
Having a good understanding of nucleation is critical for the control of many important processes, such as polymorph selection during crystallization. However, a complete picture of the molecular-level mechanisms of...
8.
Roy J, Heath S, Wang S, Ramkrishna D
Sci Rep
. 2022 Nov;
12(1):20098.
PMID: 36418377
The in-depth understanding of the dynamics of COVID-19 transmission among different age groups is of great interest for governments and health authorities so that strategies can be devised to reduce...
9.
Pandey A, Estepp J, Raja R, Guolian Kang , Ramkrishna D
Pharmaceutics
. 2022 May;
14(5).
PMID: 35631651
Sickle cell disease (SCD) is a chronic hemolytic anemia affecting millions worldwide with acute and chronic clinical manifestations and early mortality. While hydroxyurea (HU) and other treatment strategies managed to...
10.
Wang S, Venkatesh A, Ramkrishna D, Narsimhan V
J Chem Phys
. 2022 May;
156(18):184108.
PMID: 35568530
A Brownian bridge is a continuous random walk conditioned to end in a given region by adding an effective drift to guide paths toward the desired region of phase space....