Doo-Hyun Kwon
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Explore the profile of Doo-Hyun Kwon including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
78
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Recent Articles
1.
Barcan G, Kwon D, Guo J, Kowalski J, Liu L, Nilson M, et al.
J Org Chem
. 2023 Mar;
88(6):3970-3974.
PMID: 36857298
Establishing the two stereocenters in the benzothiazepine ring of linerixibat (GSK2330672) has been a long-standing problem at GSK. Our solution rests on an episulfonium-controlled Ritter reaction followed by a sulfoxide-directed...
2.
Maley S, Kwon D, Rollins N, Stanley J, Sydora O, Bischof S, et al.
Chem Sci
. 2021 Jun;
11(35):9665-9674.
PMID: 34094231
The use of data science tools to provide the emergence of non-trivial chemical features for catalyst design is an important goal in catalysis science. Additionally, there is currently no general...
3.
Kattamuri P, Bhakta U, Siriwongsup S, Kwon D, Alemany L, Yousufuddin M, et al.
J Org Chem
. 2019 Apr;
84(11):7066-7099.
PMID: 31009563
Herein, we present a general synthetic strategy for the preparation of 3-, 4-, 5-, and 6-membered heterocyclic unnatural amino acid derivatives by exploiting facile Mannich-type reactions between readily available N-alkyl-...
4.
Kattamuri P, Yin J, Siriwongsup S, Kwon D, Ess D, Li Q, et al.
J Am Chem Soc
. 2019 Feb;
141(7):3315.
PMID: 30724562
No abstract available.
5.
Behnke N, Kielawa R, Kwon D, Ess D, Kurti L
Org Lett
. 2018 Dec;
20(24):8064-8068.
PMID: 30525689
A method for the primary electrophilic amination of primary, secondary, and tertiary organometallic substrates from a bench-stable NH-oxaziridine reagent is described. This facile and highly chemoselective transformation occurs at ambient...
6.
Saavedra D, Rencher B, Kwon D, Smith S, Ess D, Andrus M
J Org Chem
. 2018 Jan;
83(4):2018-2026.
PMID: 29342353
Deoxypodophyllotoxin is a secondary metabolite lignan possessing potent anticancer activity with potential as a precursor for known anticancer drugs, but its use is limited by scarcity from natural sources. We...
7.
Kattamuri P, Yin J, Siriwongsup S, Kwon D, Ess D, Li Q, et al.
J Am Chem Soc
. 2017 Jun;
139(32):11184-11196.
PMID: 28648054
Given the importance of amines in a large number of biologically active natural products, active pharmaceutical ingredients, agrochemicals, and functional materials, the development of efficient C-N bond-forming methods with wide...
8.
Gao H, Zhou Z, Kwon D, Coombs J, Jones S, Behnke N, et al.
Nat Chem
. 2017 Jun;
9(7):681-688.
PMID: 28644470
Arylmetals are highly valuable carbon nucleophiles that are readily and inexpensively prepared from aryl halides or arenes and widely used on both laboratory and industrial scales to react directly with...
9.
Cho C, Kim B, Kwon D
Arch Orthop Trauma Surg
. 2016 Mar;
136(6):763-70.
PMID: 26965695
Introduction: We evaluated the outcomes of coracoclavicular (CC) augmentation using a suture button device with additional temporary pin fixation for acute acromioclavicular (AC) joint dislocation. Materials And Methods: Thirty-six consecutive...
10.
Kelly C, Kwon D, Ferguson M, Bischof S, Sydora O, Ess D, et al.
Angew Chem Int Ed Engl
. 2015 Oct;
54(48):14498-502.
PMID: 26448263
A crystallographically characterized three-coordinate, formally 14 electron Pt(II) complex 1 featuring terminal amido ligation is reported. Computational analysis revealed relatively weak π donation from the amide lone pair to platinum...