Donna Yu
Overview
Explore the profile of Donna Yu including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
816
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Recent Articles
1.
Su J, Zhang Q, Qi H, Wu L, Li Y, Yu D, et al.
Oncotarget
. 2017 Sep;
8(33):54378-54387.
PMID: 28903349
Gpbar1 (TGR5), a G-protein-coupled bile acid membrane receptor, is well known for its roles in regulation of glucose metabolism and energy homeostasis. In the current work, we found that TGR5...
2.
Ding L, Sousa K, Jin L, Dong B, Kim B, Ramirez R, et al.
Hepatology
. 2016 Jun;
64(3):760-73.
PMID: 27312543
Unlabelled: Vertical sleeve gastrectomy (VSG) is one of the most commonly performed clinical bariatric surgeries used for the remission of obesity and diabetes. However, the precise molecular mechanism by which...
3.
Guo C, Qi H, Yu Y, Zhang Q, Su J, Yu D, et al.
Front Pharmacol
. 2015 Dec;
6:287.
PMID: 26696888
Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well-known for its roles in regulation of energy homeostasis and glucose metabolism. Here, we show that mice lacking TGR5 were much more...
4.
Guo C, Su J, Li Z, Xiao R, Wen J, Li Y, et al.
Oncotarget
. 2015 Sep;
6(33):34402-13.
PMID: 26417930
Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. Here we show that TGR5 is a suppressor of...
5.
Lou G, Ma X, Fu X, Meng Z, Zhang W, Wang Y, et al.
PLoS One
. 2014 Apr;
9(4):e93567.
PMID: 24755711
GPBAR1/TGR5 is a novel plasma membrane-bound G protein-coupled bile acid (BA) receptor. BAs are known to induce the expression of inflammatory cytokines in the liver with unknown mechanism. Here we...
6.
Yu D, Mattern D, Forman B
Steroids
. 2012 Sep;
77(13):1335-8.
PMID: 22999992
The active, potent, and selective Farnesoid X Receptor (FXR) agonist 6α-ethylchenodeoxycholic acid (6ECDCA) has been synthesized in improved yield compared to the published methodologies. The synthesis employed selective oxidation of...
7.
Chen W, Yu D, Forman B, Huang W, Wang Y
Hepatology
. 2012 Aug;
57(2):656-66.
PMID: 22911633
Unlabelled: Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 activation also inhibits nuclear factor κB (NF-κB)-mediated...
8.
Zhang L, Li T, Yu D, Forman B, Huang W
Mol Endocrinol
. 2011 Dec;
26(1):27-36.
PMID: 22135065
Acute lung injury and its more severe form, acute respiratory distress syndrome, are characterized by an acute inflammatory response in the airspaces and lung parenchyma. The nuclear receptor farnesoid X...
9.
Wang Y, Chen W, Yu D, Forman B, Huang W
Hepatology
. 2011 Jul;
54(4):1421-32.
PMID: 21735468
Unlabelled: Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays strong attenuation of macrophage reactivity...
10.
Chen W, Wang Y, Zhang L, Shiah S, Wang M, Yang F, et al.
Hepatology
. 2009 Dec;
51(3):953-62.
PMID: 19998409
Unlabelled: Elucidating the mechanism of liver regeneration could lead to life-saving therapy for a large number of patients, especially elderly patients, after segmental liver transplantation or resection of liver tumors....