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Dongjun Ren

Explore the profile of Dongjun Ren including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1750
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Recent Articles
1.
Coy-Dibley J, Jayaraj N, Ren D, Pacifico P, Belmadani A, Wang Y, et al.
Neurobiol Pain . 2025 Jan; 17:100176. PMID: 39811188
Painful diabetic neuropathy (PDN) is a challenging complication of diabetes with patients experiencing a painful and burning sensation in their extremities. Existing treatments provide limited relief without addressing the underlying...
2.
Coy-Dibley J, Jayaraj N, Ren D, Pacifico P, Belmadani A, Wang Y, et al.
bioRxiv . 2024 Sep; PMID: 39229068
Painful diabetic neuropathy (PDN) is a challenging complication of diabetes with patients experiencing a painful and burning sensation in their extremities. Existing treatments provide limited relief without addressing the underlying...
3.
George D, Jayaraj N, Pacifico P, Ren D, Sriram N, Miller R, et al.
Pain . 2023 Dec; 165(5):1154-1168. PMID: 38147415
Painful diabetic neuropathy (PDN) is one of the most common and intractable complications of diabetes. Painful diabetic neuropathy is characterized by neuropathic pain accompanied by dorsal root ganglion (DRG) nociceptor...
4.
Wong Y, Jayaraj N, Belton T, Shum G, Ball H, Ren D, et al.
Proc Natl Acad Sci U S A . 2023 Oct; 120(44):e2313010120. PMID: 37878717
Inter-organelle contact sites between mitochondria and lysosomes mediate the crosstalk and bidirectional regulation of their dynamics in health and disease. However, mitochondria-lysosome contact sites and their misregulation have not been...
5.
Vroman R, Hunter R, Wood M, Davis O, Malfait Z, George D, et al.
Front Mol Neurosci . 2023 Sep; 16:1232447. PMID: 37664243
The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome. The ECM plays pivotal roles in...
6.
Obeidat A, Wood M, Adamczyk N, Ishihara S, Li J, Wang L, et al.
Nat Commun . 2023 Apr; 14(1):2479. PMID: 37120427
Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking and climbing stairs. Piezo2 has been implicated in the...
7.
Hopkins B, Masuho I, Ren D, Iyamu I, Lv W, Malik N, et al.
Mol Pharmacol . 2022 Jul; 102(3):128-138. PMID: 35809897
Chemokines such as stromal derived factor 1 and their G protein coupled receptors are well-known regulators of the development and functions of numerous tissues. C-X-C motif chemokine ligand 12 (CXCL12)...
8.
George D, Hackelberg S, Jayaraj N, Ren D, Edassery S, Rathwell C, et al.
Pain . 2021 Jul; 163(3):560-578. PMID: 34232927
Painful diabetic neuropathy (PDN) is an intractable complication affecting 25% of diabetic patients. Painful diabetic neuropathy is characterized by neuropathic pain accompanied by dorsal root ganglion (DRG) nociceptor hyperexcitability, resulting...
9.
Ishihara S, Obeidat A, Wokosin D, Ren D, Miller R, Malfait A, et al.
Arthritis Res Ther . 2021 Apr; 23(1):103. PMID: 33827672
Background: C-C chemokine receptor 2 (CCR2) signaling plays a key role in pain associated with experimental murine osteoarthritis (OA) after destabilization of the medial meniscus (DMM). Here, we aimed to...
10.
Jayaraj N, Bhattacharyya B, Belmadani A, Ren D, Rathwell C, Hackelberg S, et al.
J Clin Invest . 2018 Mar; 128(6):2205-2225. PMID: 29533926
Painful diabetic neuropathy (PDN) is an intractable complication of diabetes that affects 25% of patients. PDN is characterized by neuropathic pain and small-fiber degeneration, accompanied by dorsal root ganglion (DRG)...