Donghyun D Lee
Overview
Explore the profile of Donghyun D Lee including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
170
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0
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Recent Articles
1.
Maccioni S, Sharma R, Lee D, Haltner A, Khanna R, Vijgen J
Adv Ther
. 2024 Jan;
41(3):932-944.
PMID: 38185778
Introduction: Cryoballoon ablation (CBA) is a standard catheter ablation technology with demonstrated clinical effectiveness for the treatment of paroxysmal atrial fibrillation (PAF); however, it can be associated with major adverse...
2.
Lee D, Komosa M, Sudhaman S, Leao R, Zhang C, Apolonio J, et al.
J Clin Invest
. 2021 Nov;
131(21).
PMID: 34720085
Aberrant activation of telomerase in human cancer is achieved by various alterations within the TERT promoter, including cancer-specific DNA hypermethylation of the TERT hypermethylated oncological region (THOR). However, the impact...
3.
Lee D, Komosa M, Nunes N, Tabori U
Curr Opin Genet Dev
. 2020 Mar;
60:17-24.
PMID: 32114294
Telomere maintenance is a hallmark of human cancer that enables replicative immortality. Most cancer cells acquire telomere maintenance by telomerase activation through expression of telomerase reverse transcriptase (TERT), a rate-limiting...
4.
Lee D, Leao R, Komosa M, Gallo M, Zhang C, Lipman T, et al.
J Clin Invest
. 2019 Apr;
129(4):1801.
PMID: 30932912
No abstract available.
5.
Lee D, Leao R, Komosa M, Gallo M, Zhang C, Lipman T, et al.
J Clin Invest
. 2018 Oct;
129(1):223-229.
PMID: 30358567
Replicative immortality is a hallmark of cancer cells governed by telomere maintenance. Approximately 90% of human cancers maintain their telomeres by activating telomerase, driven by the transcriptional upregulation of telomerase...