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Dongchan Yang

Explore the profile of Dongchan Yang including associated specialties, affiliations and a list of published articles. Areas
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Citations 419
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Recent Articles
1.
Park J, Cho Y, Yang D, Yang H, Lee D, Kubo M, et al.
J Allergy Clin Immunol . 2023 Oct; 153(1):132-145. PMID: 37783432
Background: Basophils are rare but important effector cells in many allergic disorders. Contrary to their early progenitors, the terminal developmental processes of basophils in which they gain their unique functional...
2.
Lee A, Kim C, Park S, Joo J, Choi B, Yang D, et al.
Sci Adv . 2023 Apr; 9(15):eabo2467. PMID: 37058563
Parkinson's disease (PD) is a progressive neurodegenerative disorder. However, cell type-dependent transcriptional regulatory programs responsible for PD pathogenesis remain elusive. Here, we establish transcriptomic and epigenomic landscapes of the substantia...
3.
Yang D, Chung T, Kim D
Bioinformatics . 2022 May; 38(14):3501-3512. PMID: 35640981
Motivation: The importance of chromatin loops in gene regulation is broadly accepted. There are mainly two approaches to predict chromatin loops: transcription factor (TF) binding-dependent approach and genomic variation-based approach....
4.
Jung I, Schmitt A, Diao Y, Lee A, Liu T, Yang D, et al.
Nat Genet . 2019 Sep; 51(10):1442-1449. PMID: 31501517
A large number of putative cis-regulatory sequences have been annotated in the human genome, but the genes they control remain poorly defined. To bridge this gap, we generate maps of...
5.
Ryu J, Kim H, Yang D, Lee A, Jung I
BMC Bioinformatics . 2019 Mar; 20(Suppl 3):127. PMID: 30925856
Background: Super-enhancers or stretch enhancers are clusters of active enhancers that often coordinate cell-type specific gene regulation during development and differentiation. In addition, the enrichment of disease-associated single nucleotide polymorphism...
6.
Min J, Yang D, Kim M, Haam K, Yoo A, Choi J, et al.
Exp Mol Med . 2018 Apr; 50(4):1. PMID: 29654313
The original version of this article unfortunately contained an error in the author name Dongchan Yang, which was incorrectly given as Dongchan Yang Sung.
7.
Min J, Yang D, Kim M, Haam K, Yoo A, Choi J, et al.
Exp Mol Med . 2018 Mar; 50(3):e458. PMID: 29546878
The spatiotemporal regulation of immune cells in lymph nodes (LNs) is crucial for mounting protective T-cell responses, which are orchestrated by dendritic cells (DCs). However, it is unclear how the...
8.
di Iulio J, Bartha I, Wong E, Yu H, Lavrenko V, Yang D, et al.
Nat Genet . 2018 Feb; 50(3):333-337. PMID: 29483654
Understanding the significance of genetic variants in the noncoding genome is emerging as the next challenge in human genomics. We used the power of 11,257 whole-genome sequences and 16,384 heptamers...
9.
Yang D, Jang I, Choi J, Kim M, Lee A, Kim H, et al.
Nucleic Acids Res . 2017 Nov; 46(D1):D52-D57. PMID: 29106613
Three-dimensional (3D) chromatin structure is an emerging paradigm for understanding gene regulation mechanisms. Hi-C (high-throughput chromatin conformation capture), a method to detect long-range chromatin interactions, allows extensive genome-wide investigation of...
10.
Kim M, Yang D, Kim M, Kim S, Kim D, Kang S
Sci Rep . 2017 Jan; 7:39804. PMID: 28059162
Homeostasis of neutrophils-the blood cells that respond first to infection and tissue injury-is critical for the regulation of immune responses and regulated through granulopoiesis, a multi-stage process by which neutrophils...