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Barbara U Schraml

Explore the profile of Barbara U Schraml including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 3862
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Recent Articles
1.
Narasimhan H, Richter M, Shakiba R, Papaioannou N, Stehle C, Ravi Rengarajan K, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(9):e2417308122. PMID: 39993193
Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in...
2.
Woelk J, Narasimhan H, Pfeifhofer-Obermair C, Schraml B, Hermann-Kleiter N
Front Immunol . 2025 Jan; 15():1404805. PMID: 39840064
Nuclear receptors regulate hematopoietic stem cells (HSCs) and peripheral immune cells in mice and humans. The nuclear orphan receptor NR2F6 (EAR-2) has been shown to control murine hematopoiesis. Still, detailed...
3.
Xiao H, Ulmert I, Bach L, Huber J, Narasimhan H, Kurochkin I, et al.
Nat Commun . 2024 Apr; 15(1):3554. PMID: 38688934
Conventional dendritic cells (cDC) play key roles in immune induction, but what drives their heterogeneity and functional specialization is still ill-defined. Here we show that cDC-specific deletion of the transcriptional...
4.
Wyczanska M, Thalmeier F, Keller U, Klaus R, Narasimhan H, Ji X, et al.
Sci Rep . 2024 Mar; 14(1):5495. PMID: 38448513
Urinary tract obstruction during renal development leads to inflammation, leukocyte infiltration, tubular cell death, and interstitial fibrosis. Interleukin-10 (IL-10) is an anti-inflammatory cytokine, produced mainly by monocytes/macrophages and regulatory T-cells....
5.
Long H, Lichtnekert J, Andrassy J, Schraml B, Romagnani P, Anders H
Front Immunol . 2023 Oct; 14:1194988. PMID: 37868987
Mononuclear phagocytes (MP), i.e., monocytes, macrophages, and dendritic cells (DCs), are essential for immune homeostasis via their capacities to clear pathogens, pathogen components, and non-infectious particles. However, tissue injury-related changes...
6.
Bayerl F, Meiser P, Donakonda S, Hirschberger A, Lacher S, Pedde A, et al.
Immunity . 2023 Jun; 56(6):1341-1358.e11. PMID: 37315536
Type 1 conventional dendritic cells (cDC1s) are critical for anti-cancer immunity. Protective anti-cancer immunity is thought to require cDC1s to sustain T cell responses within tumors, but it is poorly...
7.
Schraml B
Science . 2023 Mar; 379(6639):1301-1302. PMID: 36996196
Neuroimmune interactions in the skin can shape the functions of dendritic cells.
8.
Bayerl F, Bejarano D, Bertacchi G, Doffin A, Gobbini E, Hubert M, et al.
Eur J Immunol . 2023 Jan; 53(11):e2249923. PMID: 36623939
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and...
9.
Probst H, Stoitzner P, Amon L, Backer R, Brand A, Chen J, et al.
Eur J Immunol . 2022 Dec; 53(11):e2249819. PMID: 36512638
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy and...
10.
Lutz K, Musumeci A, Sie C, Dursun E, Winheim E, Bagnoli J, et al.
Nat Commun . 2022 Jun; 13(1):3456. PMID: 35705536
Plasmacytoid and conventional dendritic cells (pDC and cDC) are generated from progenitor cells in the bone marrow and commitment to pDCs or cDC subtypes may occur in earlier and later...