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Dong Yun Yang

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Articles 12
Citations 455
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Recent Articles
1.
Guo H, Wang R, Bai Y, Yang D
Gene . 2013 Jul; 527(1):430-3. PMID: 23810940
Brachydactyly is a relatively common congenital abnormality and can be associated with many other malformations. However, brachydactyly in association with absence of nasal bone is rare. Two Chinese siblings with...
2.
Matsuo K, Gray M, Yang D, Srivastava S, Tripathi P, Sonoda L, et al.
Gynecol Oncol . 2012 Dec; 128(3):552-9. PMID: 23200913
Objective: Currently, accurately identifying endometrial cancer patients at high risk for recurrence remains poor. To ascertain if changes in the endoplasmic reticulum (ER) stress marker, glucose-regulated-protein-78 (GRP78) can serve as...
3.
Park H, Cho J, Lim E, Lee C, Lee S, Seo S, et al.
Differentiation . 2011 Jul; 82(3):136-43. PMID: 21764208
A single cell division is governed by the catalytic reactions of cyclins and cyclin-dependent kinases (CDKs). Stem cells are unique in that they can differentiate into tissue-specific cell types (lineage...
4.
Kuramochi H, Tanaka K, Oh D, Lehman B, Dunst C, Yang D, et al.
Int J Oncol . 2007 Dec; 32(1):201-8. PMID: 18097560
Thymidylate synthase (TS) is known to have polymorphisms in the 5' and 3' untranslated region (UTR). These polymorphisms have been reported to be associated with high TS expression and chemoresistance...
5.
Zhang W, Press O, Haiman C, Yang D, Gordon M, Fazzone W, et al.
J Clin Oncol . 2007 Aug; 25(24):3726-31. PMID: 17704422
Purpose: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme regulating intracellular folate levels, which affects DNA synthesis and methylation. Two MTHFR gene polymorphisms, C677T and A1298C, are linked to altered enzyme...
6.
Zhang W, Gordon M, Schultheis A, Yang D, Nagashima F, Azuma M, et al.
J Clin Oncol . 2007 Aug; 25(24):3712-8. PMID: 17704420
Purpose: Cetuximab, a chimeric immunoglobulin G 1 (IgG1) anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb), has shown efficacy in 10% of patients with metastatic colorectal cancer (CRC). Recent studies...
7.
Vallbohmer D, Yang D, Kuramochi H, Shimizu D, Danenberg K, Lindebjerg J, et al.
Int J Oncol . 2007 Jul; 31(2):413-8. PMID: 17611699
Capecitabine is a fluoropyrimidine-based drug that offers physicians a more convenient treatment for advanced colorectal cancer (CRC), with manageable toxicity and antitumor activity comparable to that of continuous-infusion therapies with...
8.
Vallbohmer D, Iqbal S, Yang D, Rhodes K, Zhang W, Gordon M, et al.
Int J Cancer . 2006 Aug; 119(10):2435-42. PMID: 16894565
Molecular markers predicting the efficacy of CPT-11 based chemotherapies in patients with colorectal cancer (CRC) are unknown. Therefore, we investigated whether mRNA levels of drug targets (Topoisomerase I, TS), enzymes...
9.
Zhang W, Gordon M, Press O, Rhodes K, Vallbohmer D, Yang D, et al.
Pharmacogenet Genomics . 2006 Jun; 16(7):475-83. PMID: 16788380
The study aimed to investigate whether polymorphisms in genes of the EGFR signaling pathway are associated with clinical outcome in advanced colorectal cancer (CRC) patients treated with single-agent Cetuximab. Polymorphisms...
10.
Vallbohmer D, Brabender J, Yang D, Danenberg K, Schneider P, Metzger R, et al.
Clin Lung Cancer . 2006 Apr; 7(5):332-7. PMID: 16640805
Background: Recent studies imply that HER2/neu is a potential prognostic factor in patients with non-small-cell lung cancer (NSCLC). Whereas considerable evidence indicates sex differences in epidemiologic, hormonal, biologic, and genetic...