Dong Chuan Wu
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Explore the profile of Dong Chuan Wu including associated specialties, affiliations and a list of published articles.
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21
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938
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Recent Articles
1.
Zeng Y, Yang K, Cui Y, Zhu X, Li R, Zhang H, et al.
Nat Commun
. 2024 Apr;
15(1):3221.
PMID: 38622129
The hippocampus creates a cognitive map of the external environment by encoding spatial and self-motion-related information. However, it is unclear whether hippocampal neurons could also incorporate internal cognitive states reflecting...
2.
Lu C, Chang H, Hsu L, Lee M, Cheng J, Wu D, et al.
Pharmaceuticals (Basel)
. 2023 Jun;
16(2).
PMID: 37259423
The NMDA receptor hypofunction has been implicated in schizophrenia, memory impairment, and Alzheimer's disease. Modulating the abundance of D-serine, a co-agonist of the NMDA receptor, is a strategy to treat...
3.
Wen Y, Dong Z, Liu J, Axerio-Cilies P, Du Y, Li J, et al.
Signal Transduct Target Ther
. 2022 Oct;
7(1):340.
PMID: 36184627
Maintaining a proper balance between the glutamate receptor-mediated neuronal excitation and the A type of GABA receptor (GABAR) mediated inhibition is essential for brain functioning; and its imbalance contributes to...
4.
Mei Y, Lee M, Cheng T, Hsiao I, Wu D, Zhou N
Neurobiol Dis
. 2020 Sep;
145:105071.
PMID: 32890774
Spreading depolarization (SD) represents a neurological process characterized by a massive, self-sustaining wave of brain cell depolarization. Understanding its mechanism is important for treating ischemic or hemorrhagic stroke and migraine...
5.
Hung T, Chu F, Wu D, Wu S, Huang C
Mol Neurobiol
. 2019 Jan;
56(8):5497-5506.
PMID: 30623373
The peroxisome proliferator-activated receptor (PPAR) family, type II nucleus receptors have been successfully tested for their neuroprotective potential in certain central nervous system diseases. The aim of the present study...
6.
Mei Y, Wu D, Zhou N
Front Psychiatry
. 2018 Nov;
9:544.
PMID: 30459650
According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated with the positive and negative symptoms of schizophrenia....
7.
Wang C, Hernandez C, Wu J, Zhou N, Hsu H, Shen M, et al.
J Neurosci
. 2018 Feb;
38(11):2818-2831.
PMID: 29440552
Hyperekplexia, an inherited neuronal disorder characterized by exaggerated startle responses with unexpected sensory stimuli, is caused by dysfunction of glycinergic inhibitory transmission. From analysis of newly identified human hyperekplexia mutations...
8.
Wu D, Chen R, Cheng T, Chiang Y, Shen M, Hsu L, et al.
Cereb Cortex
. 2017 Oct;
28(9):3204-3216.
PMID: 28981616
Spreading depression (SD) is a pathophysiological phenomenon characterized by propagating waves of profound neuronal and glial depolarization in central nervous system gray matter. Although SD is primarily mediated by neurons...
9.
Lin C, Hsu S, Cheng T, Huang C, Chiang Y, Hsiao I, et al.
Sci Rep
. 2017 Sep;
7(1):11884.
PMID: 28928441
Epilepsy and spreading depolarization (SD) are both episodic brain disorders and often exist together in the same individual. In CA1 pyramidal neurons of mouse hippocampal slices, induction of SD evoked...
10.
Shen M, Wang C, Lin C, Zhou N, Kao S, Wu D
Sci Rep
. 2016 Sep;
6:32756.
PMID: 27595800
Airway mucus overproduction is one of the most common symptoms of asthma that causes severe clinical outcomes in patients. Despite the effectiveness of general asthma therapies, specific treatments that prevent...