Dong-Kee Lee
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Explore the profile of Dong-Kee Lee including associated specialties, affiliations and a list of published articles.
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22
Citations
1007
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Recent Articles
1.
Liu H, He Y, Liu H, Brouwers B, Yin N, Lawler K, et al.
Sci Adv
. 2024 Jun;
10(26):eadl2675.
PMID: 38941473
Declined memory is a hallmark of Alzheimer's disease (AD). Experiments in rodents and human postmortem studies suggest that serotonin (5-hydroxytryptamine, 5-HT) plays a role in memory, but the underlying mechanisms...
2.
He Y, Brouwers B, Liu H, Liu H, Lawler K, Mendes de Oliveira E, et al.
Nat Med
. 2022 Dec;
28(12):2537-2546.
PMID: 36536256
Serotonin reuptake inhibitors and receptor agonists are used to treat obesity, anxiety and depression. Here we studied the role of the serotonin 2C receptor (5-HTR) in weight regulation and behavior....
3.
Ding Y, Liu Y, Lee D, Tong Z, Yu X, Li Y, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(21).
PMID: 34006643
HER2-positive (HER2) breast cancers (BrCs) contain approximately equal numbers of ERαHER2 and ERαHER2 cases. An enduring obstacle is the unclear cell lineage-related characteristics of these BrCs. Although ERαHER2 BrCs could...
4.
Zhang B, Ci X, Tao R, Ni J, Xuan X, King J, et al.
Nat Commun
. 2020 Feb;
11(1):997.
PMID: 32081850
Prostate development depends on balanced cell proliferation and differentiation, and acetylated KLF5 is known to alter epithelial proliferation. It remains elusive whether post-translational modifications of transcription factors can differentially determine...
5.
Lee D, Liu Y, Liao L, Li W, Danielpour D, Xu J
Cell Res
. 2019 Feb;
29(5):420-422.
PMID: 30778177
No abstract available.
6.
Yang Y, Riccio P, Schotsaert M, Mori M, Lu J, Lee D, et al.
Dev Cell
. 2018 Mar;
44(6):752-761.e4.
PMID: 29587145
Basal cells (BCs) are p63-expressing multipotent progenitors of skin, tracheoesophageal and urinary tracts. p63 is abundant in developing airways; however, it remains largely unclear how embryonic p63 cells contribute to...
7.
Sreekumar A, Toneff M, Toh E, Roarty K, Creighton C, Belka G, et al.
Dev Cell
. 2017 Nov;
43(4):436-448.e6.
PMID: 29103953
Puberty is characterized by dynamic tissue remodeling in the mammary gland involving ductal elongation, resolution into the mature epithelial bilayer, and lumen formation. To decipher the cellular mechanisms underlying these...
8.
Xu Y, Lee D, Feng Z, Xu Y, Bu W, Li Y, et al.
Proc Natl Acad Sci U S A
. 2017 Oct;
114(43):11494-11499.
PMID: 29073077
Twist1 is an epithelial-mesenchymal transition (EMT)-inducing transcription factor (TF) that promotes cell migration and invasion. To determine the intrinsic role of Twist1 in EMT and breast cancer initiation, growth, and...
9.
Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, et al.
Nature
. 2017 Oct;
550(7677):529-533.
PMID: 29019984
In several organ systems, the transitional zone between different types of epithelium is a hotspot for pre-neoplastic metaplasia and malignancy, but the cells of origin for these metaplastic epithelia and...
10.
Xi Y, Kim T, Brumwell A, Driver I, Wei Y, Tan V, et al.
Nat Cell Biol
. 2017 Jul;
19(8):904-914.
PMID: 28737769
After influenza infection, lineage-negative epithelial progenitors (LNEPs) exhibit a binary response to reconstitute epithelial barriers: activating a Notch-dependent ΔNp63/cytokeratin 5 (Krt5) remodelling program or differentiating into alveolar type II cells...