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Donald W Everett

Explore the profile of Donald W Everett including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 4
Citations 93
Followers 0
Related Specialties
Pharmacology
Endocrinology
Top 10 Co-Authors
Donglu Zhang
W Griffith Humphreys
Peter T Cheng
Lifei Wang
Yongjun Xue
Jos H Beijnen
Rogelio Mosqueda-Garcia
Jan H Beumer
Hao Zhang
Arun Swaminathan
Published In
Drug Metab Dispos
Drug Metab Pharmacokinet
Affiliations
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Recent Articles
1.
Biotransformation profiling of [(14)C]ixabepilone in human plasma, urine and feces samples using accelerator mass spectrometry (AMS)
Comezoglu S, Ly V, Zhang D, Humphreys W, Bonacorsi S, Everett D, et al.
Drug Metab Pharmacokinet . 2010 Jan; 24(6):511-22. PMID: 20045986
Ixabepilone (BMS-247550, Ixempra is a semi-synthetic analog of the natural product epothilone B and marketed for its use in the treatment of cancer. A conventional human ADME study using decay...
2.
Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites
Li W, Zhang D, Wang L, Zhang H, Cheng P, Zhang D, et al.
Drug Metab Dispos . 2006 Feb; 34(5):807-20. PMID: 16467134
Muraglitazar (Pargluva; Bristol-Myers Squibb), a dual alpha/gamma peroxisome proliferator-activated receptor activator, is under development for treatment of type 2 diabetes. This study describes the biotransformation profile of carbon-14-labeled muraglitazar in...
3.
Glucuronidation as a major metabolic clearance pathway of 14c-labeled muraglitazar in humans: metabolic profiles in subjects with or without bile collection
Wang L, Zhang D, Swaminathan A, Xue Y, Cheng P, Wu S, et al.
Drug Metab Dispos . 2005 Dec; 34(3):427-39. PMID: 16381667
The metabolism and disposition of 14C-labeled muraglitazar (Pargluva), a novel dual alpha/gamma peroxisome proliferator-activated receptor activator, was investigated in eight healthy male subjects with and without bile collection (groups 1...
4.
In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation
Zhang D, Chando T, Everett D, Patten C, Dehal S, Humphreys W
Drug Metab Dispos . 2005 Aug; 33(11):1729-39. PMID: 16118329
Several human immunodeficiency virus (HIV) protease inhibitors, including atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir, were tested for their potential to inhibit uridine 5'-diphospho-glucuronosyltransferase (UGT) activity. Experiments were performed with...