Donald T Gracias
Overview
Explore the profile of Donald T Gracias including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
581
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sethi G, Gracias D, Gupta R, Carr D, Miki H, Da Silva Antunes R, et al.
Allergy
. 2023 Mar;
78(8):2168-2180.
PMID: 36951658
Background: Exacerbations of asthma are thought to be strongly dependent on reactivation of allergen-induced lung tissue-resident and circulatory memory CD4 T cells. Strategies that broadly inhibit multiple T cell populations...
2.
Dolina J, Lee J, Moore E, Hope J, Gracias D, Matsutani T, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(10):e2113329119.
PMID: 35239442
SignificanceThe CD4 T response following acute infection is heterogeneous and deploys two distinct modes of suppression coinciding with initial pathogen exposure and resolution of infection. This bimodal suppression of CD8...
3.
Gupta R, Gracias D, Figueroa D, Miki H, Miller J, Fung K, et al.
Sci Immunol
. 2021 Nov;
6(65):eabi8823.
PMID: 34797693
TNF and IL-17 are two cytokines that drive dysregulated keratinocyte activity, and their targeting is highly efficacious in patients with psoriasis, but whether these molecules act with other inflammatory factors...
4.
Gracias D, Sethi G, Mehta A, Miki H, Gupta R, Yagita H, et al.
J Allergy Clin Immunol
. 2020 Nov;
147(6):2316-2329.
PMID: 33160971
Background: The selective reduction of memory T2 cell responses could be key to affording tolerance and protection from the recurrence of damaging allergic pathology. Objective: We asked whether TNF family...
5.
Hope J, Stairiker C, Spantidea P, Gracias D, Carey A, Fike A, et al.
Front Immunol
. 2018 Jan;
8:1696.
PMID: 29358931
We report here that the expression of the transcription factor T-bet, which is known to be required for effector cytotoxic CD8 T lymphocytes (CTL) generation and effector memory cell formation,...
6.
Mehta A, Gracias D, Croft M
Cytokine
. 2016 Aug;
101:14-18.
PMID: 27531077
TNF (tumor necrosis factor) is both a pro-inflammatory and anti-inflammatory cytokine that is central to the development of autoimmune disease, cancer, and protection against infectious pathogens. As well as a...
7.
Carey A, Gracias D, Thayer J, Boesteanu A, Kumova O, Mueller Y, et al.
J Immunol
. 2016 Feb;
196(6):2602-13.
PMID: 26873987
Currently, there is little consensus regarding the most appropriate animal model to study acute infection and the virus-specific CD8(+) T cell (CTL) responses in neonates. TCRβ high-throughput sequencing in naive...
8.
Gracias D, Boesteanu A, Fraietta J, Hope J, Carey A, Mueller Y, et al.
J Immunol
. 2016 Jan;
196(3):1186-98.
PMID: 26740110
The p110δ isoform of PI3K is known to play an important role in immunity, yet its contribution to CTL responses has not been fully elucidated. Using murine p110δ-deficient CD8(+) T...
9.
Johnson B, Fraietta J, Gracias D, Hope J, Stairiker C, Patel P, et al.
Nanotoxicology
. 2014 Nov;
9(6):737-48.
PMID: 25378273
The increasing risk of incidental exposure to nanomaterials has led to mounting concerns regarding nanotoxicity. Zinc oxide nanoparticles (ZnO NPs) are produced in large quantities and have come under scrutiny...
10.
Fraietta J, Mueller Y, Yang G, Boesteanu A, Gracias D, Do D, et al.
PLoS Pathog
. 2013 Oct;
9(10):e1003658.
PMID: 24130482
The role of Type I interferon (IFN) during pathogenic HIV and SIV infections remains unclear, with conflicting observations suggesting protective versus immunopathological effects. We therefore examined the effect of IFNα/β...