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Donald J Hagler Jr

Explore the profile of Donald J Hagler Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 110
Citations 5579
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Recent Articles
11.
Parekh P, Fan C, Frei O, Palmer C, Smith D, Makowski C, et al.
Hum Brain Mapp . 2024 Feb; 45(2):e26579. PMID: 38339910
The linear mixed-effects model (LME) is a versatile approach to account for dependence among observations. Many large-scale neuroimaging datasets with complex designs have increased the need for LME; however LME...
12.
Maleyeff L, Newburger J, Wypij D, Thomas N, Anagnoustou E, Brueckner M, et al.
Ann Clin Transl Neurol . 2023 Nov; 11(2):278-290. PMID: 38009418
Objective: Persons with congenital heart disease (CHD) are at increased risk of neurodevelopmental disabilities, including impairments to executive function. Sulcal pattern features correlate with executive function in adolescents with single-ventricle...
13.
Makowski C, Brown T, Zhao W, Hagler Jr D, Parekh P, Garavan H, et al.
bioRxiv . 2023 Jul; PMID: 37398195
Magnetic resonance imaging (MRI) is a popular and useful non-invasive method to map patterns of brain structure and function to complex human traits. Recently published observations in multiple large scale...
14.
Williams M, Elman J, Bell T, Dale A, Eyler L, Fennema-Notestine C, et al.
Neurobiol Aging . 2023 Jun; 129:185-194. PMID: 37343448
Some evidence suggests a biphasic pattern of changes in cortical thickness wherein higher, rather than lower, thickness is associated with very early Alzheimer's disease (AD) pathology. We examined whether integrating...
15.
Tang R, Elman J, Dale A, Dorros S, Eyler L, Fennema-Notestine C, et al.
J Gerontol A Biol Sci Med Sci . 2023 Apr; 79(1). PMID: 37096346
Background: Childhood disadvantage is a prominent risk factor for cognitive and brain aging. Childhood disadvantage is associated with poorer episodic memory in late midlife and functional and structural brain abnormalities...
16.
Franz C, Gustavson D, Elman J, Fennema-Notestine C, Hagler Jr D, Baraff A, et al.
J Alzheimers Dis . 2023 Mar; 93(1):193-209. PMID: 36970897
Background: Fine particulate matter (PM2.5) and nitrogen dioxide (NO2) measures of ambient air pollution are associated with accelerated age-related cognitive impairment, and Alzheimer's disease and related dementias (ADRD). Objective: We...
17.
Morton S, Norris-Brilliant A, Cunningham S, King E, Goldmuntz E, Brueckner M, et al.
JAMA Netw Open . 2023 Jan; 6(1):e2253191. PMID: 36701153
Importance: Neurodevelopmental disabilities are commonly associated with congenital heart disease (CHD), but medical and sociodemographic factors explain only one-third of the variance in outcomes. Objective: To examine whether potentially damaging...
18.
Tang R, Elman J, Franz C, Dale A, Eyler L, Fennema-Notestine C, et al.
Geroscience . 2022 Oct; 45(2):837-849. PMID: 36269506
Executive function encompasses effortful cognitive processes that are particularly susceptible to aging. Functional brain networks supporting executive function-such as the frontoparietal control network and the multiple demand system-have been extensively...
19.
Williams M, Gillespie N, Bell T, Dale A, Elman J, Eyler L, et al.
Biol Psychiatry Cogn Neurosci Neuroimaging . 2022 Jun; 8(9):918-927. PMID: 35738479
Background: Composite scores of magnetic resonance imaging-derived metrics in brain regions associated with Alzheimer's disease (AD), commonly termed AD signatures, have been developed to distinguish early AD-related atrophy from normal...
20.
Fan C, Loughnan R, Makowski C, Pecheva D, Chen C, Hagler Jr D, et al.
Nat Commun . 2022 May; 13(1):2423. PMID: 35505052
The molecular determinants of tissue composition of the human brain remain largely unknown. Recent genome-wide association studies (GWAS) on this topic have had limited success due to methodological constraints. Here,...